HitPredict

Interactor 1: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Interactor 2: KLK5 (Q9Y337)
Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme)
Gene: KLK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 293
+	Hs
		1309540 TBA1C_HUMAN (1-451): 0: 726: 98.00		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		933677 TBA4A_HUMAN (1-450): 0: 717: 96.00		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		428515 TBB5_HUMAN (1-439): 0: 695: 40.77		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		934035 TBB4B_HUMAN (1-437): 0: 693: 40.50		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		714751 TBA1B_HUMAN (1-440): 0: 715: 99.55		TRY3_HUMAN (54-293): 2.93e-111: 325: 43.57
+	Hs
		1309527 TBA1C_HUMAN (1-451): 0: 726: 98.00		KLK11_HUMAN (64-292): 2.13e-101: 299: 50.43
+	Hs
		933653 TBA4A_HUMAN (1-450): 0: 717: 96.00		KLK11_HUMAN (64-292): 2.13e-101: 299: 50.43
+	Hs
		933689 TBA4A_HUMAN (1-450): 0: 717: 96.00		ST14_HUMAN (27-288): 1.3e-94: 299: 32.50
+	Hs
		1309491 TBA1C_HUMAN (1-451): 0: 726: 98.00		KLK15_HUMAN (57-292): 1.13e-97: 289: 40.08
+	Hs
		1175223 TBA1A_HUMAN (1-440): 0: 713: 100.00		KLK11_HUMAN (64-292): 2.13e-101: 299: 50.43
+	Hs
		933554 TBA4A_HUMAN (1-450): 0: 717: 96.00		KLK6_HUMAN (64-291): 1.92e-98: 290: 44.98
+	Hs
		933613 TBA4A_HUMAN (1-450): 0: 717: 96.00		KLK15_HUMAN (57-292): 1.13e-97: 289: 40.08
+	Hs
		1175174 TBA1A_HUMAN (1-440): 0: 713: 100.00		KLK15_HUMAN (57-292): 1.13e-97: 289: 40.08
+	Hs
		1348218 TBA8_HUMAN (1-440): 0: 701: 90.68		KLK12_HUMAN (60-292): 1.41e-93: 278: 44.49
+	Hs
		933221 TBA1B_HUMAN (1-440): 0: 715: 99.55		PRSS8_HUMAN (51-289): 8.32e-35: 130: 35.63