Protein: GFI1B
Zinc finger protein Gfi-1b (Growth factor independent protein 1B) (Potential regulator of CDKN1A translocated in CML)

Gene: GFI1B
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q5VTD9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

246662

KDM1A
Lysine-specific histone demethylase 1A

4

7

Small-scale

0.702

High

1217776

RCOR1
REST corepressor 1

3

7

Small-scale

0.664

High

238819

KALRN
Kalirin

1

2

High-throughput

0.656

High

1217747

HDAC2
Histone deacetylase 2

2

8

Small-scale

0.601

High

1217756

EHMT2
Histone-lysine N-methyltransferase EHMT2

2

9

Small-scale

0.601

High

1217778

JAG2
Protein jagged-2

1

17

High-throughput

0.573

High

1154524

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.541

High

1217750

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

1217770

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.541

High

1217758

NELL2
Protein kinase C-binding protein NELL2

1

20

High-throughput

0.523

High

1217765

CPAP
Centrosomal P4.1-associated protein

1

1

High-throughput

0.523

High

764825

CTNB1
Catenin beta-1

1

7

Small-scale

0.515

High

903390

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

3

Small-scale

0.515

High

1047835

TLE1
Transducin-like enhancer protein 1

1

6

Small-scale

0.515

High

1047997

TLE3
Transducin-like enhancer protein 3

1

6

Small-scale

0.515

High

1109804

HDAC1
Histone deacetylase 1

1

8

Small-scale

0.515

High

1217741

RCOR2
REST corepressor 2

1

7

Small-scale

0.515

High

1217742

CCAR2
Cell cycle and apoptosis regulator protein 2

1

3

Small-scale

0.515

High

1217766

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

3

Small-scale

0.515

High

1217772

RCOR3
REST corepressor 3

1

7

Small-scale

0.515

High

136912

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

16

High-throughput

0.508

High

169589

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

4

High-throughput

0.508

High

451520

CENPB
Major centromere autoantigen B

1

13

High-throughput

0.508

High

462887

LAMB1
Laminin subunit beta-1

1

15

High-throughput

0.508

High

555702

ACTN1
Alpha-actinin-1

1

1

High-throughput

0.508

High

572016

TRI27
Zinc finger protein RFP

1

20

High-throughput

0.508

High

639753

TAF1
Transcription initiation factor TFIID subunit 1

1

10

High-throughput

0.508

High

681406

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.508

High

705397

GRN
Progranulin

1

2

High-throughput

0.508

High

799202

BRCA1
Breast cancer type 1 susceptibility protein

1

17

High-throughput

0.508

High

846339

MATR3
Matrin-3

1

1

High-throughput

0.508

High

857476

NOTC1
Neurogenic locus notch homolog protein 1

1

20

High-throughput

0.508

High

965720

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

High-throughput

0.508

High

1010853

TMF1
TATA element modulatory factor

1

1

High-throughput

0.508

High

1022543

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

2

High-throughput

0.508

High

1061738

TLE5
TLE family member 5

1

6

High-throughput

0.508

High

1093848

TRAF1
TNF receptor-associated factor 1

1

9

High-throughput

0.508

High

1151532

TRIP6
Thyroid receptor-interacting protein 6

1

2

High-throughput

0.508

High

1217724

TENS2
Tensin-2

1

1

High-throughput

0.508

High

1217736

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

20

High-throughput

0.508

High

1217740

PHC2
Polyhomeotic-like protein 2

1

1

High-throughput

0.508

High

1217751

RNF31
E3 ubiquitin-protein ligase RNF31

1

17

High-throughput

0.508

High

1217752

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.508

High

1217754

AJUBA
LIM domain-containing protein ajuba

1

7

High-throughput

0.508

High

1217760

LZTS2
Leucine zipper putative tumor suppressor 2

1

8

High-throughput

0.508

High

1217762

GRIP2
Glutamate receptor-interacting protein 2

1

4

High-throughput

0.508

High

1217763

TSYL2
Testis-specific Y-encoded-like protein 2

1

8

High-throughput

0.508

High

1217767

PICK1
PRKCA-binding protein

1

8

High-throughput

0.508

High

1217773

FBLN5
Fibulin-5

1

20

High-throughput

0.508

High

1217775

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

High-throughput

0.508

High

1217781

DTNA
Dystrobrevin alpha

1

3

High-throughput

0.508

High

1217744

USBP1
Harmonin-binding protein USHBP1

1

6

High-throughput

0.494

High

1217761

BEGIN
Brain-enriched guanylate kinase-associated protein

1

1

High-throughput

0.494

High

1217726

CDC73
Parafibromin

1

0

Small-scale

0.493

High

1217729

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

High-throughput

0.486

High

1217757

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.486

High

1217768

DZAN1
Double zinc ribbon and ankyrin repeat-containing protein 1

1

0

High-throughput

0.486

High

1217769

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.486

High

1217777

ZNRF3
E3 ubiquitin-protein ligase ZNRF3

1

0

High-throughput

0.486

High

1068836

IFFO1
Non-homologous end joining factor IFFO1

1

3

High-throughput

0.481

High

1217723

MYOME
Myomegalin

1

2

High-throughput

0.481

High

216458

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

7

Small-scale

0.479

High

270250

MTG16
Protein CBFA2T3

1

1

Small-scale

0.479

High

322665

KDM4B
Lysine-specific demethylase 4B

1

3

Small-scale

0.479

High

325876

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

Small-scale

0.479

High

668623

APC
Adenomatous polyposis coli protein

1

6

Small-scale

0.479

High

879177

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

1103222

CTBP1
C-terminal-binding protein 1

1

3

Small-scale

0.479

High

1217734

KDM3B
Lysine-specific demethylase 3B

1

1

Small-scale

0.479

High

1217746

KDM2B
Lysine-specific demethylase 2B

1

3

Small-scale

0.479

High

1217748

CBP
CREB-binding protein

1

13

Small-scale

0.479

High

1217764

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

Small-scale

0.479

High

1217780

KDM2A
Lysine-specific demethylase 2A

1

4

Small-scale

0.479

High

1217782

SPIN1
Spindlin-1

1

2

Small-scale

0.479

High

270524

MEGF6
Multiple epidermal growth factor-like domains protein 6

1

20

High-throughput

0.464

High

351552

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

20

High-throughput

0.464

High

654515

FBLN1
Fibulin-1

1

20

High-throughput

0.464

High

1086415

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

20

High-throughput

0.464

High

1202480

RUN3A
RUN domain-containing protein 3A

1

1

High-throughput

0.464

High

1217728

TXD11
Thioredoxin domain-containing protein 11

1

3

High-throughput

0.464

High

1217730

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

1

4

High-throughput

0.464

High

1217731

PDZD4
PDZ domain-containing protein 4

1

3

High-throughput

0.464

High

1217732

HECW1
E3 ubiquitin-protein ligase HECW1

1

1

High-throughput

0.464

High

1217735

MYH14
Myosin-14

1

1

High-throughput

0.464

High

1217739

RFIP4
Rab11 family-interacting protein 4

1

2

High-throughput

0.464

High

1217743

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

20

High-throughput

0.464

High

1217749

NELL1
Protein kinase C-binding protein NELL1

1

20

High-throughput

0.464

High

1217753

PDLI5
PDZ and LIM domain protein 5

1

2

High-throughput

0.464

High

1217755

CC136
Coiled-coil domain-containing protein 136

1

5

High-throughput

0.464

High

1217759

ATX2
Ataxin-2

1

2

High-throughput

0.464

High

1217771

KIF17
Kinesin-like protein KIF17

1

5

High-throughput

0.464

High

1217774

EGFL7
Epidermal growth factor-like protein 7

1

4

High-throughput

0.464

High

1144569

PTPA
Serine/threonine-protein phosphatase 2A activator

1

0

Small-scale

0.458

High

1217779

RUVB1
RuvB-like 1

1

0

Small-scale

0.458

High

1217737

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

1

High-throughput

0.439

High

106092

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1217727

Q6P593
IFFO1 protein

1

1

High-throughput

0.417

High

1217745

Q8NDD3
Uncharacterized protein DKFZp586M1819

1

1

High-throughput

0.417

High

979415

VISL1
Visinin-like protein 1

1

0

High-throughput

0.265

Low

1126702

BECN1
Beclin-1

1

0

High-throughput

0.265

Low

1217725

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.265

Low

1217733

BEND5
BEN domain-containing protein 5

1

0

High-throughput

0.265

Low

1217738

MON1A
Vacuolar fusion protein MON1 homolog A

1

0

High-throughput

0.265

Low

1215438

Q5TB27
Phosphodiesterase 4D interacting protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025