HitPredict

Interactor 1: RPH3L (Q768S4)
Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein)
Gene: Rph3al

Interactor 2: RB27B (Q99P58)
Ras-related protein Rab-27B (EC 3.6.5.2)
Gene: Rab27b

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12578829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0006887 - exocytosis GO:0030141 - secretory granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Mm			1 218
+	Rn
		222478 RPH3L_RAT (1-302): 1.07e-112: 329: 92.38		RAB3A_RAT (2-218): 6.28e-91: 267: 38.71
+	Mm
		926078 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RAB3A_MOUSE (2-218): 6.28e-91: 267: 38.71
+	Mm
		919017 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RAB3C_MOUSE (2-218): 1.33e-89: 264: 39.45
+	Mm
		722683 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RAB3D_MOUSE (2-218): 7.35e-85: 252: 41.48
+	Hs
		119876 RPH3L_HUMAN (1-293): 2.62e-106: 313: 82.99		RB27B_HUMAN (1-218): 6.6e-86: 255: 94.50
+	Mm
		877194 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RAB8A_MOUSE (2-217): 4.03e-79: 237: 38.43
+	Mm
		1176143 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RB27A_MOUSE (1-218): 2.01e-77: 233: 71.49
+	Hs
		845960 RPH3L_HUMAN (1-293): 2.62e-106: 313: 82.99		RB27A_HUMAN (1-218): 9.36e-80: 239: 70.14
+	Hs
		591501 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RAB3A_HUMAN (2-218): 1.31e-90: 267: 38.71
+	Mm
		812772 RP3A_MOUSE (1-295): 1.75e-87: 276: 38.04		RAB3A_MOUSE (2-218): 6.28e-91: 267: 38.71
+	Mm
		812771 RP3A_MOUSE (1-295): 1.75e-87: 276: 38.04		RAB3C_MOUSE (2-218): 1.33e-89: 264: 39.45
+	Hs
		119877 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RB27B_HUMAN (1-218): 6.6e-86: 255: 94.50
+	Mm
		812776 RP3A_MOUSE (1-295): 1.75e-87: 276: 38.04		RB27B_MOUSE (1-218): 2.42e-85: 253: 100.00
+	Mm
		722679 RP3A_MOUSE (1-295): 1.75e-87: 276: 38.04		RAB3D_MOUSE (2-218): 7.35e-85: 252: 41.48
+	Hs
		845961 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RB27A_HUMAN (1-218): 9.36e-80: 239: 70.14
+	Hs
		1273014 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RAB8B_HUMAN (2-217): 1.63e-79: 238: 37.50
+	Hs
		894828 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RAB8A_HUMAN (2-216): 1.54e-79: 238: 38.61
+	Mm
		812770 RP3A_MOUSE (1-295): 1.75e-87: 276: 38.04		RAB8A_MOUSE (2-217): 4.03e-79: 237: 38.43
+	Mm
		1176142 RPH3L_MOUSE (1-302): 1.1e-112: 329: 100.00		RAB3B_MOUSE (2-218): 7.3e-54: 173: 38.99
+	Hs
		591719 RP3A_HUMAN (1-301): 6.81e-90: 283: 37.24		RAB3B_HUMAN (2-218): 1.28e-52: 170: 38.53