HitPredict

Interactor 1: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1435 Hs			1 449
+	Hs
		933248 ASXL2_HUMAN (1-1435): 0: 650: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428270 ASXL2_HUMAN (1-1435): 0: 650: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933863 ASXL2_HUMAN (1-1435): 0: 650: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		990921 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		990875 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428157 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1220816 ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		933344 ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		933263 ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		92120 NACAM_HUMAN (731-1397): 1.16e-13: 78.5: 10.35		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		933252 MICA3_HUMAN (309-913): 6.55e-13: 76.2: 15.72		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Dm
		415626 FUTSC_DROME (75-1360): 9.19e-10: 65.8: 10.34		TBA1_DROME (1-439): 0: 714: 97.27
+	Dm
		415643 FUTSC_DROME (75-1360): 9.19e-10: 65.8: 10.34		TBA2_DROME (1-449): 0: 713: 94.66
+	Hs
		428416 ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		428292 ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933962 ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Dm
		415665 FUTSC_DROME (75-1360): 9.19e-10: 65.8: 10.34		TBA3_DROME (1-439): 0: 710: 96.81
+	Hs
		933882 ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31		TBB4B_HUMAN (1-437): 0: 697: 40.73