Protein: VATA
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)

Gene: VATA, ATP6V1A
Organism: Homo sapiens
Interactions: 221
UniProt ID: P38606

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636998

VATB2
V-type proton ATPase subunit B, brain isoform

10

18

Small-scale

0.967

High

800601

VATD
V-type proton ATPase subunit D

4

8

High-throughput

0.892

High

583062

VATB1
V-type proton ATPase subunit B, kidney isoform

4

17

High-throughput

0.886

High

784777

VATE1
V-type proton ATPase subunit E 1

3

10

High-throughput

0.839

High

800498

VATF
V-type proton ATPase subunit F

2

7

High-throughput

0.789

High

800536

VATC2
V-type proton ATPase subunit C 2

5

10

High-throughput

0.712

High

276820

VATG1
V-type proton ATPase subunit G 1

4

11

High-throughput

0.683

High

292574

RENR
Renin receptor

3

2

High-throughput

0.662

High

800549

VPP1
V-type proton ATPase 116 kDa subunit a 1

3

13

Small-scale

0.650

High

800589

VATH
V-type proton ATPase subunit H

3

7

High-throughput

0.643

High

49508

TLDC2
TLD domain-containing protein 2

1

8

High-throughput

0.618

High

800463

RAB7A
Ras-related protein Rab-7a

2

9

Small-scale

0.611

High

800474

VA0D1
V-type proton ATPase subunit d 1

2

7

Small-scale

0.611

High

800484

CUL3
Cullin-3

2

2

High-throughput

0.611

High

637093

VATC1
V-type proton ATPase subunit C 1

2

10

High-throughput

0.601

High

800554

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

3

High-throughput

0.601

High

800568

CHM4B
Charged multivesicular body protein 4b

2

5

High-throughput

0.601

High

240947

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

400408

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

3

High-throughput

0.584

High

341200

VATG2
V-type proton ATPase subunit G 2

2

11

High-throughput

0.571

High

800491

KPCD1
Serine/threonine-protein kinase D1

2

6

High-throughput

0.571

High

800503

LTOR1
Ragulator complex protein LAMTOR1

2

3

Small-scale

0.571

High

800525

S35F6
Solute carrier family 35 member F6

2

3

High-throughput

0.552

High

64940

ARRD5
Arrestin domain-containing protein 5

1

3

High-throughput

0.536

High

361151

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

529244

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.536

High

800462

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.536

High

800493

VAMP3
Vesicle-associated membrane protein 3

1

6

High-throughput

0.536

High

800494

VAS1
V-type proton ATPase subunit S1

1

1

High-throughput

0.536

High

800501

TM63B
Mechanosensitive cation channel TMEM63B

1

3

High-throughput

0.536

High

800513

RRAGA
Ras-related GTP-binding protein A

1

3

High-throughput

0.536

High

800520

STX12
Syntaxin-12

1

4

High-throughput

0.536

High

800565

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.536

High

800574

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.536

High

800583

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.536

High

800598

GOT1B
Vesicle transport protein GOT1B

1

2

High-throughput

0.536

High

105482

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

800555

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

405408

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

627930

ANXA7
Annexin A7

1

6

High-throughput

0.508

High

800454

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.508

High

800496

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

507626

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.501

High

800471

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.501

High

800497

DREB
Drebrin

1

4

High-throughput

0.489

High

125288

LEG9
Galectin-9

1

6

High-throughput

0.479

High

178203

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

217910

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

247716

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

259550

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

293314

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

345458

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

405858

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

411492

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

519800

ANDR
Androgen receptor

1

6

High-throughput

0.479

High

541376

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.479

High

560317

IFM1
Interferon-induced transmembrane protein 1

1

5

High-throughput

0.479

High

588079

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

606347

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

633887

ATP4A
Potassium-transporting ATPase alpha chain 1

1

2

Small-scale

0.479

High

651196

CBL
E3 ubiquitin-protein ligase CBL

1

2

High-throughput

0.479

High

694794

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

731030

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

767573

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

788856

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

800456

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

800458

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

800459

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.479

High

800460

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

800464

RAB9A
Ras-related protein Rab-9A

1

9

High-throughput

0.479

High

800475

1433G
14-3-3 protein gamma

1

8

High-throughput

0.479

High

800476

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

800478

SKP1
S-phase kinase-associated protein 1

1

3

Small-scale

0.479

High

800479

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

800480

IFM3
Interferon-induced transmembrane protein 3

1

5

High-throughput

0.479

High

800481

TP4A2
Protein tyrosine phosphatase type IVA 2

1

3

Small-scale

0.479

High

800483

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

800486

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.479

High

800488

CUL7
Cullin-7

1

1

High-throughput

0.479

High

800495

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.479

High

800502

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

800509

LMTK1
Serine/threonine-protein kinase LMTK1

1

7

High-throughput

0.479

High

800512

RHOU
Rho-related GTP-binding protein RhoU

1

4

High-throughput

0.479

High

800516

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

800518

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

800523

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

800531

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

800532

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

800539

BICD2
Protein bicaudal D homolog 2

1

3

High-throughput

0.479

High

800545

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

800546

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

800547

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

800550

ARMC5
Armadillo repeat-containing protein 5

1

3

High-throughput

0.479

High

800553

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

800560

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

800563

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

3

High-throughput

0.479

High

800564

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

800566

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

4

Small-scale

0.479

High

800569

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

800570

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

800575

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

800576

S38A7
Sodium-coupled neutral amino acid transporter 7

1

2

Small-scale

0.479

High

800577

ARL8B
ADP-ribosylation factor-like protein 8B

1

9

High-throughput

0.479

High

800584

SYLC
Leucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

800588

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

800591

YETS2
YEATS domain-containing protein 2

1

1

High-throughput

0.479

High

800594

FAF1
FAS-associated factor 1

1

2

High-throughput

0.479

High

330423

LC7L3
Luc7-like protein 3

1

0

High-throughput

0.458

High

379916

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

800472

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

800487

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

800490

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

800507

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

800544

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

800580

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

800602

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.458

High

76664

B4E1J8
ADP-ribosylation factor-like protein 8B

1

8

High-throughput

0.445

High

85188

B7Z6L9
V-type proton ATPase subunit

1

7

High-throughput

0.445

High

95850

E7EMK3
Flotillin

1

7

High-throughput

0.445

High

186409

TM9S1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.445

High

211120

CTR4
Cationic amino acid transporter 4

1

2

High-throughput

0.445

High

227820

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.445

High

273495

DJC13
DnaJ homolog subfamily C member 13

1

5

High-throughput

0.445

High

285604

BAF
Barrier-to-autointegration factor

1

1

High-throughput

0.445

High

299091

FLOT1
Flotillin-1

1

7

High-throughput

0.445

High

318282

MYO1D
Unconventional myosin-Id

1

4

High-throughput

0.445

High

369445

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.445

High

390477

TFR1
Transferrin receptor protein 1

1

2

High-throughput

0.445

High

391579

FRIH
Ferritin heavy chain

1

3

High-throughput

0.445

High

402338

GBA1
Lysosomal acid glucosylceramidase

1

1

High-throughput

0.445

High

404711

PRIO
Major prion protein

1

1

High-throughput

0.445

High

429432

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

456203

CATD
Cathepsin D

1

2

High-throughput

0.445

High

477408

CD63
CD63 antigen

1

3

High-throughput

0.445

High

486544

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.445

High

520677

RRAS
Ras-related protein R-Ras

1

7

High-throughput

0.445

High

538537

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

4

High-throughput

0.445

High

539867

RALB
Ras-related protein Ral-B

1

5

High-throughput

0.445

High

540336

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.445

High

561930

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.445

High

563342

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

574078

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

4

High-throughput

0.445

High

609609

LEG3
Galectin-3

1

6

High-throughput

0.445

High

641921

CD9
CD9 antigen

1

3

High-throughput

0.445

High

690190

STOM
Stomatin

1

6

High-throughput

0.445

High

731761

S10AB
Protein S100-A11

1

1

High-throughput

0.445

High

800455

S26A3
Chloride anion exchanger

1

1

High-throughput

0.445

High

800457

S19A1
Reduced folate transporter

1

1

High-throughput

0.445

High

800461

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.445

High

800466

VAMP7
Vesicle-associated membrane protein 7

1

4

High-throughput

0.445

High

800467

CTR2
Cationic amino acid transporter 2

1

2

High-throughput

0.445

High

800468

IST1
IST1 homolog

1

1

High-throughput

0.445

High

800470

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.445

High

800477

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

3

High-throughput

0.445

High

800482

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

13

High-throughput

0.445

High

800485

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.445

High

800492

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.445

High

800500

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

800504

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

800506

PLBL1
Phospholipase B-like 1

1

1

High-throughput

0.445

High

800514

CHM1B
Charged multivesicular body protein 1b

1

14

High-throughput

0.445

High

800517

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.445

High

800519

UN93A
Protein unc-93 homolog A

1

2

High-throughput

0.445

High

800524

TM192
Transmembrane protein 192

1

2

High-throughput

0.445

High

800526

LAT4
Large neutral amino acids transporter small subunit 4

1

2

High-throughput

0.445

High

800530

S38A9
Neutral amino acid transporter 9

1

1

High-throughput

0.445

High

800533

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.445

High

800540

MOT10
Monocarboxylate transporter 10

1

4

High-throughput

0.445

High

800541

MITD1
MIT domain-containing protein 1

1

1

High-throughput

0.445

High

800542

MYO3B
Myosin-IIIb

1

3

High-throughput

0.445

High

800543

NICA
Nicastrin

1

1

High-throughput

0.445

High

800548

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.445

High

800551

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

800556

PKP4
Plakophilin-4

1

3

High-throughput

0.445

High

800557

ZBT18
Zinc finger and BTB domain-containing protein 18

1

2

High-throughput

0.445

High

800558

SC6A7
Sodium-dependent proline transporter

1

4

High-throughput

0.445

High

800559

VAMP8
Vesicle-associated membrane protein 8

1

6

High-throughput

0.445

High

800561

S46A2
Solute carrier family 46 member 2

1

4

High-throughput

0.445

High

800562

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

800567

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.445

High

800571

RRAGC
Ras-related GTP-binding protein C

1

3

High-throughput

0.445

High

800572

CHM1A
Charged multivesicular body protein 1a

1

12

High-throughput

0.445

High

800581

MYOF
Myoferlin

1

1

High-throughput

0.445

High

800582

CHMP5
Charged multivesicular body protein 5

1

10

High-throughput

0.445

High

800585

RHCG
Ammonium transporter Rh type C

1

1

High-throughput

0.445

High

800586

S53A1
Solute carrier family 53 member 1

1

5

High-throughput

0.445

High

800587

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.445

High

800590

RB22A
Ras-related protein Rab-22A

1

9

High-throughput

0.445

High

800592

S6A14
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

1

4

High-throughput

0.445

High

800593

STX8
Syntaxin-8

1

2

High-throughput

0.445

High

800595

FLVC2
Choline/ethanolamine transporter FLVCR2

1

1

High-throughput

0.445

High

800596

CHM2B
Charged multivesicular body protein 2b

1

14

High-throughput

0.445

High

800597

ITM2B
Integral membrane protein 2B

1

3

High-throughput

0.445

High

800599

CHMP3
Charged multivesicular body protein 3

1

14

High-throughput

0.445

High

800600

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

13

High-throughput

0.445

High

353054

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

800489

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.437

High

800510

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

800528

EFCB3
EF-hand calcium-binding domain-containing protein 3

1

3

High-throughput

0.437

High

800578

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

337074

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

388383

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

800465

GPC3
Glypican-3

1

0

High-throughput

0.426

High

800469

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.426

High

800473

SMS
Somatostatin

1

0

Small-scale

0.426

High

800499

SC5AC
Sodium-coupled monocarboxylate transporter 2

1

0

High-throughput

0.426

High

800505

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

800508

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.426

High

800527

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.426

High

800535

VGLU3
Vesicular glutamate transporter 3

1

0

High-throughput

0.426

High

800537

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.426

High

800573

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

800529

S43A3
Equilibrative nucleobase transporter 1

1

2

High-throughput

0.407

High

800552

Q96HY3
EF-hand calcium-binding domain-containing protein 11

1

2

High-throughput

0.407

High

800579

TMOD3
Tropomodulin-3

1

3

High-throughput

0.407

High

800534

MACA2
Putative tyrosine carboxypeptidase MATCAP2

1

0

High-throughput

0.269

Low

800511

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

800515

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

800521

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.249

Low

800522

DRC2
Dynein regulatory complex subunit 2

1

0

High-throughput

0.249

Low

800538

CAGE1
Cancer-associated gene 1 protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025