HitPredict

Interactor 1: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36180891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1435 Hs			1 305
+	Hs
		903326 ASXL2_HUMAN (1-1435): 0: 650: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		1319305 ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34		SKI8_HUMAN (1-305): 2.86e-101: 300: 100.00
+	Hs
		990904 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		1056932 MDC1_HUMAN (105-1326): 8.13e-25: 115: 9.03		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		1281391 PRR36_HUMAN (82-1095): 1.14e-17: 91.6: 10.73		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		152678 KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		209436 MDC1_HUMAN (105-1326): 8.13e-25: 115: 9.03		PLRG1_HUMAN (4-217): 2.47e-43: 156: 22.52
+	Hs
		152622 KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903498 ASXL3_HUMAN (72-1435): 5.5e-14: 79.7: 12.34		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903355 ASXL1_HUMAN (333-1435): 1.06e-13: 78.5: 12.31		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Mm
		903669 KMT2C_MOUSE (633-1085): 5.48e-12: 73.3: 12.29		WDR5_MOUSE (179-304): 4.63e-41: 147: 33.33
+	Hs
		152663 KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50		WDR5B_HUMAN (179-304): 1.89e-37: 137: 30.95
+	Dm
		1370339 Q9VLS7_DROME (362-1082): 5.85e-10: 66.4: 12.21		FBXW7_DROME (217-304): 3.53e-19: 89.8: 24.72
+	Dm
		1370295 Q9VLS7_DROME (362-1082): 5.85e-10: 66.4: 12.21		POC1_DROME (219-305): 1.82e-18: 86.6: 24.14