Protein: ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial (ATP synthase F1 subunit alpha)

Gene: ATPA, Atp5f1a
Organism: Mus musculus
Interactions: 125
UniProt ID: Q03265

Gene Ontology (top 5):
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0002020 - protease binding
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

204364

ATIF1
ATPase inhibitor, mitochondrial

4

3

Small-scale

0.873

High

940816

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

3

15

High-throughput

0.827

High

1021427

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

3

5

High-throughput

0.827

High

1042117

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

3

13

High-throughput

0.827

High

1042161

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

3

8

High-throughput

0.827

High

1042178

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

3

7

High-throughput

0.827

High

1042194

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

3

7

High-throughput

0.827

High

1042188

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

2

9

High-throughput

0.754

High

469598

MDHM
Malate dehydrogenase, mitochondrial

3

6

High-throughput

0.640

High

940637

ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial

3

1

High-throughput

0.640

High

1042168

ECHB
Trifunctional enzyme subunit beta, mitochondrial

3

5

High-throughput

0.640

High

1042169

ACON
Aconitate hydratase, mitochondrial

3

6

High-throughput

0.640

High

1042155

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

2

High-throughput

0.618

High

397827

ATP8
ATP synthase F(0) complex subunit 8

2

2

High-throughput

0.584

High

426389

AATM
Aspartate aminotransferase, mitochondrial

2

2

High-throughput

0.584

High

1042171

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

2

4

High-throughput

0.584

High

1042189

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

2

13

High-throughput

0.584

High

1042193

ETFB
Electron transfer flavoprotein subunit beta

2

3

High-throughput

0.584

High

1042118

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

7

High-throughput

0.536

High

509040

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

8

Small-scale

0.501

High

59606

A2AM57
Inversin

1

3

High-throughput

0.489

High

204865

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

9

High-throughput

0.479

High

625171

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.479

High

628295

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

2

High-throughput

0.479

High

801616

HSPA9
Stress-70 protein, mitochondrial

1

5

High-throughput

0.479

High

837344

ECI1
Enoyl-CoA delta isomerase 1, mitochondrial

1

11

High-throughput

0.479

High

853086

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

866540

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

868811

CACP
Carnitine O-acetyltransferase

1

2

High-throughput

0.479

High

878132

ADT1
ADP/ATP translocase 1

1

7

High-throughput

0.479

High

902368

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

914832

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

2

High-throughput

0.479

High

926031

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

High-throughput

0.479

High

972207

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.479

High

989439

CH60
60 kDa heat shock protein, mitochondrial

1

8

High-throughput

0.479

High

1021916

FUMH
Fumarate hydratase, mitochondrial

1

3

High-throughput

0.479

High

1023519

PRDX5
Peroxiredoxin-5, mitochondrial

1

1

High-throughput

0.479

High

1037831

MYH6
Myosin-6

1

3

High-throughput

0.479

High

1042124

ABCD2
ATP-binding cassette sub-family D member 2

1

4

High-throughput

0.479

High

1042125

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

1042132

NEB2
Neurabin-2

1

9

High-throughput

0.479

High

1042134

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

2

High-throughput

0.479

High

1042137

Q7TMG8
Glioblastoma amplified sequence

1

2

High-throughput

0.479

High

1042139

Q80X68
Citrate synthase

1

7

High-throughput

0.479

High

1042141

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

1042143

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

6

High-throughput

0.479

High

1042144

ECHM
Enoyl-CoA hydratase, mitochondrial

1

9

High-throughput

0.479

High

1042146

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

8

High-throughput

0.479

High

1042149

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

5

High-throughput

0.479

High

1042151

Q8C1W8
NAD(P) transhydrogenase, mitochondrial

1

1

High-throughput

0.479

High

1042154

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

1042156

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

2

High-throughput

0.479

High

1042157

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.479

High

1042158

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

5

High-throughput

0.479

High

1042159

S25A3
Solute carrier family 25 member 3

1

9

High-throughput

0.479

High

1042160

Q91VA7
Isocitrate dehydrogenase [NAD] subunit, mitochondrial

1

8

High-throughput

0.479

High

1042162

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

1042163

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1042165

EED
Polycomb protein EED

1

7

High-throughput

0.479

High

1042170

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

2

High-throughput

0.479

High

1042172

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

4

High-throughput

0.479

High

1042174

FBX32
F-box only protein 32

1

3

High-throughput

0.479

High

1042175

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

1

High-throughput

0.479

High

1042176

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

1

High-throughput

0.479

High

1042177

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

9

High-throughput

0.479

High

1042179

ACO13
Acyl-coenzyme A thioesterase 13

1

1

High-throughput

0.479

High

1042180

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

14

High-throughput

0.479

High

1042181

CISY
Citrate synthase, mitochondrial

1

7

High-throughput

0.479

High

1042183

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

3

High-throughput

0.479

High

1042184

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

1

High-throughput

0.479

High

1042185

ERP44
Endoplasmic reticulum resident protein 44

1

4

Small-scale

0.479

High

1042187

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

7

High-throughput

0.479

High

1042190

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

1042195

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

1042197

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

8

High-throughput

0.479

High

1042200

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

485916

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

912404

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.458

High

967289

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.458

High

1042119

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

1042136

MIC27
MICOS complex subunit Mic27

1

0

High-throughput

0.458

High

1042140

MFN1
Mitofusin-1

1

0

High-throughput

0.458

High

1042145

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.458

High

1042166

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.458

High

1042167

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.458

High

1042173

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.458

High

1042182

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

0

High-throughput

0.458

High

1042186

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.458

High

1042191

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

1042192

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

1042198

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

0

High-throughput

0.458

High

1042201

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.458

High

591041

KPCE
Protein kinase C epsilon type

1

4

Small-scale

0.445

High

651516

CBL
E3 ubiquitin-protein ligase CBL

1

5

High-throughput

0.445

High

999056

1433F
14-3-3 protein eta

1

14

High-throughput

0.445

High

1021682

THIOM
Thioredoxin, mitochondrial

1

8

High-throughput

0.445

High

1042121

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.445

High

1042126

DLG4
Disks large homolog 4

1

2

High-throughput

0.445

High

1042153

FTM
Protein fantom

1

5

High-throughput

0.445

High

1042199

B9D1
B9 domain-containing protein 1

1

1

Small-scale

0.445

High

108653

G3X9H5
Huntingtin

1

4

High-throughput

0.437

High

398360

CFAD
Complement factor D

1

1

High-throughput

0.437

High

789722

THB
Thyroid hormone receptor beta

1

4

High-throughput

0.437

High

944134

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

8

Small-scale

0.437

High

1042120

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

5

High-throughput

0.437

High

1042122

RBM27
RNA-binding protein 27

1

6

High-throughput

0.437

High

1042123

CLU
Clustered mitochondria protein homolog

1

1

High-throughput

0.437

High

1042127

INADL
InaD-like protein

1

5

Small-scale

0.437

High

1042128

TFE3
Transcription factor E3

1

3

High-throughput

0.437

High

1042130

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.437

High

1042133

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

8

High-throughput

0.437

High

1042135

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.437

High

1042138

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.437

High

1042142

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.437

High

1042147

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.437

High

1042150

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.437

High

1042152

MT21E
Protein-lysine methyltransferase METTL21E

1

4

High-throughput

0.437

High

883763

CENPC
Centromere protein C

1

5

High-throughput

0.407

High

1042129

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.407

High

1042148

RD3
Protein RD3

1

1

Small-scale

0.407

High

1042164

RAB31
Ras-related protein Rab-31

1

6

Small-scale

0.407

High

1042196

F16P1
Fructose-1,6-bisphosphatase 1

1

4

Small-scale

0.407

High

877763

TNNI3
Troponin I, cardiac muscle

1

0

High-throughput

0.249

Low

1042131

Q6GTZ3
Idb1 protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025