HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient, affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1063 Hs			1 530
+	Hs
		117551 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		297392 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		522631 MYH7_HUMAN (4-1060): 0: 1068: 27.29		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1270020 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		64608 MYH7B_HUMAN (8-1045): 0: 1034: 26.67		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1270044 MYH4_HUMAN (5-1045): 0: 1032: 26.70		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		214461 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368902 MYH6_HUMAN (4-1060): 0: 1050: 26.70		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370802 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		724944 MYH9_HUMAN (5-974): 0: 994: 29.37		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369096 MYH9_HUMAN (5-974): 0: 994: 29.37		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		297268 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377299 MYO7A_HUMAN (8-973): 0: 1056: 31.23		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377795 MYH2_HUMAN (5-1045): 0: 1045: 26.83		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		117569 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		587127 MYH9_HUMAN (5-974): 0: 994: 29.37		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		297279 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		214481 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487871 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487836 MYO5B_HUMAN (46-959): 0: 970: 30.60		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59