HitPredict

Interactor 1: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Interactor 2: DTNA (Q9Y4J8)
Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)
Gene: DTNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	36736316, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 788 Hs			1 743
+	Hs
		647997 MARK3_HUMAN (3-788): 0: 656: 60.40		DTNA_HUMAN (1-743): 0: 900: 100.00
+	Hs
		1349681 MARK1_HUMAN (3-788): 0: 644: 63.22		DTNA_HUMAN (1-743): 0: 900: 100.00
+	Hs
		246458 MARK2_HUMAN (1-788): 0: 790: 100.00		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Hs
		513876 MARK2_HUMAN (1-788): 0: 790: 100.00		DMD_HUMAN (14-646): 8.85e-170: 543: 25.65
+	Hs
		246425 MARK3_HUMAN (3-788): 0: 656: 60.40		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Hs
		809137 MARK2_HUMAN (1-788): 0: 790: 100.00		UTRN_HUMAN (14-655): 4.26e-164: 527: 23.82
+	Hs
		246502 MARK1_HUMAN (3-788): 0: 644: 63.22		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Hs
		647842 MARK3_HUMAN (3-788): 0: 656: 60.40		UTRN_HUMAN (14-655): 4.26e-164: 527: 23.82
+	Hs
		809189 MARK1_HUMAN (3-788): 0: 644: 63.22		UTRN_HUMAN (14-655): 4.26e-164: 527: 23.82
+	Hs
		319892 MARK2_HUMAN (1-788): 0: 790: 100.00		HERC2_HUMAN (219-610): 2.19e-40: 162: 15.62