HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: MILK1 (Q8N3F8)
MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Gene: MICALL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0006897 - endocytosis GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 863
+	Hs
		892482 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		951148 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00
+	Hs
		1183465 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		892491 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		951163 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93
+	Hs
		297809 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297834 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297819 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		297827 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		K0754_HUMAN (202-848): 3.19e-64: 238: 13.56
+	Hs
		436258 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		963394 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164556 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		963356 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		892322 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		950929 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69
+	Hs
		164633 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		164589 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		164602 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92
+	Hs
		918915 RAB1A_HUMAN (39-256): 5.65e-82: 246: 21.92		MICA1_HUMAN (377-811): 1.09e-42: 170: 18.40
+	Hs
		892450 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00