HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: PKHA1 (Q9HB21)
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)
Gene: PLEKHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 404
+	Hs
		436517 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Hs
		1296739 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Hs
		892605 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Hs
		951355 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		PKHA1_HUMAN (1-404): 6.66e-121: 358: 100.00
+	Dd
		710120 RACB_DICDI (48-239): 2.34e-91: 269: 52.08		PAKC_DICDI (194-284): 2.83e-34: 134: 38.71
+	Hs
		1056347 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		RASA3_HUMAN (177-323): 3.74e-34: 136: 23.93
+	Hs
		1296737 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		1183557 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		892375 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		RASA3_HUMAN (177-323): 3.74e-34: 136: 23.93
+	Hs
		892610 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		MYO10_HUMAN (193-334): 1.54e-33: 135: 21.09
+	Hs
		892603 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		951352 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		PKHA5_HUMAN (130-342): 3.73e-33: 133: 20.55
+	Hs
		892677 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		ASAP1_HUMAN (41-306): 5.83e-32: 130: 11.59
+	Hs
		436587 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		FARP1_HUMAN (29-347): 7e-10: 63.1: 13.04
+	Hs
		1296772 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		FARP1_HUMAN (29-347): 7e-10: 63.1: 13.04
+	Hs
		440941 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		PLEK_HUMAN (190-293): 1.27e-11: 67.5: 31.43
+	Hs
		892516 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		ARAP2_HUMAN (210-301): 1.82e-11: 68.1: 14.74
+	Hs
		1167375 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		MPRIP_HUMAN (203-403): 2.81e-10: 64.3: 16.26
+	Hs
		1183622 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		FARP1_HUMAN (29-347): 7e-10: 63.1: 13.04
+	Hs
		892698 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		FARP1_HUMAN (29-347): 7e-10: 63.1: 13.04