HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 1771
+	Hs
		436568 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		1296761 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		892676 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		951454 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		925723 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		914450 RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		901042 RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		545696 RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		894580 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		564734 RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		1330985 RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		1021421 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		950953 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		925238 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		900423 RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		893947 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		925204 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		ANK2_HUMAN (3-233): 5.93e-53: 208: 25.11
+	Hs
		862018 RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87		DAPK1_HUMAN (4-305): 4.92e-35: 149: 31.58