HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: SH3B4 (Q9P0V3)
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)
Gene: SH3BP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 963
+	Hs
		436551 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		1296755 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		892646 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		951423 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		925686 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		900996 RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		545671 RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		894531 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		564715 RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		1330962 RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26		SH3B4_HUMAN (1-963): 0: 1835: 100.00