HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: E41L3 (Q9Y2J2)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: EPB41L3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 1087
+	Hs
		892690 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		951471 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		436277 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		PTN13_HUMAN (4-988): 4.66e-130: 440: 16.62
+	Hs
		436519 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		1296740 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		1020186 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		PTN13_HUMAN (4-988): 4.66e-130: 440: 16.62
+	Hs
		892339 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		PTN13_HUMAN (4-988): 4.66e-130: 440: 16.62
+	Hs
		1183560 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		892609 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		951359 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Hs
		436587 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		1296772 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		1183622 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		892698 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		951489 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		FARP1_HUMAN (73-662): 1.4e-114: 381: 28.31
+	Hs
		505620 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		EPB41_HUMAN (701-1083): 3.49e-41: 166: 33.33
+	Hs
		436506 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33
+	Hs
		1183552 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33
+	Hs
		892594 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33
+	Hs
		951337 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33