Interactor 1: TM10C (Q7L0Y3)
tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221)
Gene: TRMT10C

Interactor 2: HCD2 (Q99714)
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH)
Gene: HSD17B10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.955

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35235311, 37071682, 18984158, 29880640
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, peptide array, molecular sieving, differential scanning calorimetry, pull down, x ray scattering
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~tRNA_m1G_MT
Common GO terms GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0030678 - mitochondrial ribonuclease P complex
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 403
Hs

1 261
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024