Interactor 1: MPK4 (Q39024)
Mitogen-activated protein kinase 4 (AtMPK4) (MAP kinase 4) (EC 2.7.11.24)
Gene: MPK4
Interactor 2: M2K2 (Q9S7U9)
Mitogen-activated protein kinase kinase 2 (AtMAP2Kbeta) (AtMKK2) (MAP kinase kinase 2) (EC 2.7.12.2)
Gene: MKK2
Species: Arabidopsis thaliana
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.957 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15225555, 32612234, 18982020, 9878570, 19513235, unassigned2354 |
| Identification Methods | two hybrid, enzymatic study, protein complementation assay, protein kinase assay, bimolecular fluorescence complementation, two hybrid array, two hybrid prey pooling approach, validated two hybrid, in-gel kinase assay |
| Interaction Type | direct interaction, phosphorylation reaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0009409 - response to cold GO:0009651 - response to salt stress GO:0045087 - innate immune response and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
