HitPredict

Interactor 1: KCTD9 (Q7L273)
BTB/POZ domain-containing protein KCTD9
Gene: KCTD9

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 728
+	Hs
		1045929 BACD2_HUMAN (67-296): 1.9e-47: 165: 21.61		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252368 BACD1_HUMAN (71-296): 3.69e-44: 157: 22.08		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1235348 KCD17_HUMAN (89-259): 5.6e-37: 137: 27.87		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252409 KCTD7_HUMAN (57-211): 3.25e-37: 137: 27.27		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1174576 KCTD1_HUMAN (50-199): 7.43e-37: 136: 21.19		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1241184 KCTD6_HUMAN (88-186): 7.72e-23: 97.8: 37.00		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		819567 KCNC1_HUMAN (85-194): 2.91e-34: 134: 30.36		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		942389 KCND2_HUMAN (50-235): 2.5e-41: 155: 18.75		DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22
+	Hs
		1020242 KCTD3_HUMAN (80-224): 1.29e-33: 134: 28.86		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Hs
		1050021 KCNB2_HUMAN (73-282): 8.64e-38: 146: 18.67		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		1057230 KCTD2_HUMAN (82-246): 2.7e-38: 140: 32.02		DLG3_HUMAN (619-713): 1.3e-14: 79.7: 28.87
+	Hs
		1050010 SHKB1_HUMAN (82-193): 4.77e-34: 135: 33.04		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		1132926 KCTD5_HUMAN (83-259): 1.16e-41: 147: 30.16		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		1057225 KCTD2_HUMAN (82-246): 2.7e-38: 140: 32.02		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		1132909 KCD17_HUMAN (89-259): 5.6e-37: 137: 27.87		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		1132910 SHKB1_HUMAN (82-193): 4.77e-34: 135: 33.04		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Hs
		1132930 KCTD3_HUMAN (80-224): 1.29e-33: 134: 28.86		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56