HitPredict

Interactor 1: G2E3 (Q7L622)
G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase)
Gene: G2E3

Interactor 2: Q86V38 (Q86V38)
Atrophin 1
Gene: ATN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 706 Hs			1 1191
+	Hs
		869556 KMT2B_HUMAN (10-128): 3.3e-33: 139: 24.37		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Hs
		869456 KMT2A_HUMAN (104-303): 7.44e-15: 80.9: 15.17		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Hs
		869494 KMT2C_HUMAN (78-314): 1.39e-10: 67.1: 15.92		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Dm
		1187409 RNO_DROME (11-140): 9.04e-33: 138: 21.43		Q9VLS7_DROME (1-859): 2.59e-14: 80.3: 9.82
+	Hs
		1243852 KMT2B_HUMAN (10-128): 3.3e-33: 139: 24.37		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		1350537 KMT2B_HUMAN (10-128): 3.3e-33: 139: 24.37		RERE_HUMAN (3-865): 1.02e-11: 71.8: 8.77
+	Hs
		301148 KDM4B_HUMAN (13-135): 2.76e-27: 120: 19.08		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		975285 KMT2A_HUMAN (104-303): 7.44e-15: 80.9: 15.17		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		975338 KMT2A_HUMAN (104-303): 7.44e-15: 80.9: 15.17		RERE_HUMAN (3-865): 1.02e-11: 71.8: 8.77
+	Hs
		152667 KMT2D_HUMAN (77-287): 2.9e-12: 72.8: 15.49		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59