Protein: POP2
Poly(A) ribonuclease POP2 (EC 3.1.13.4) (CCR4-associated factor 1)

Gene: POP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P39008

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0004535 - poly(A)-specific ribonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636136

NOT1
General negative regulator of transcription subunit 1

16

8

Small-scale

0.988

High

680029

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

21

14

Small-scale

0.769

High

759095

CAF40
Protein CAF40

12

5

Small-scale

0.760

High

713691

NOT4
General negative regulator of transcription subunit 4

9

3

Small-scale

0.748

High

409839

NOT2
General negative regulator of transcription subunit 2

5

9

Small-scale

0.710

High

409992

NOT3
General negative regulator of transcription subunit 3

4

6

Small-scale

0.693

High

759108

NOT5
General negative regulator of transcription subunit 5

4

6

Small-scale

0.672

High

759094

CF130
Protein CAF130

4

0

Small-scale

0.667

High

759080

MPT5
Suppressor protein MPT5

3

9

Small-scale

0.666

High

759082

DHH1
ATP-dependent RNA helicase DHH1

2

3

Small-scale

0.639

High

605532

DBF2
Cell cycle protein kinase DBF2

3

0

Small-scale

0.622

High

759103

MRB1
Methylated RNA-binding protein 1

2

6

Small-scale

0.600

High

488491

PRI1
DNA primase small subunit

2

0

High-throughput

0.595

High

526843

DPOLA
DNA polymerase alpha catalytic subunit A

2

0

High-throughput

0.595

High

593807

PRI2
DNA primase large subunit

2

0

High-throughput

0.595

High

744521

DPOA2
DNA polymerase alpha subunit B

2

0

High-throughput

0.595

High

629422

PUF4
Pumilio homology domain family member 4

2

9

Small-scale

0.595

High

728239

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.588

High

759086

NACB2
Nascent polypeptide-associated complex subunit beta-2

2

1

Small-scale

0.584

High

539247

YAK1
Dual specificity protein kinase YAK1

1

4

Small-scale

0.578

High

700892

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

493980

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

511328

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

759087

MOB1
DBF2 kinase activator protein MOB1

1

0

Small-scale

0.549

High

566582

VATA
V-type proton ATPase catalytic subunit A

2

1

High-throughput

0.537

High

676051

XPO1
Exportin-1

1

1

High-throughput

0.536

High

713286

WHI3
Protein WHI3

1

0

High-throughput

0.518

High

759096

NST1
Stress response protein NST1

1

0

High-throughput

0.518

High

759092

CTH2
mRNA decay factor CTH2

1

4

Small-scale

0.515

High

526237

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.513

High

759098

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

759099

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

Small-scale

0.508

High

376788

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

Small-scale

0.501

High

756672

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.493

High

759093

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.493

High

759109

DCP1
mRNA-decapping enzyme subunit 1

1

0

Small-scale

0.493

High

410523

CATT
Catalase T

1

0

High-throughput

0.486

High

759101

CSI1
Cop9 signalosome-interactor 1

1

0

High-throughput

0.486

High

759091

CTH1
mRNA decay factor CTH1

1

4

Small-scale

0.481

High

425471

TFS2
Transcription elongation factor S-II

1

0

Small-scale

0.480

High

549814

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

Small-scale

0.480

High

550547

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.480

High

593065

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.480

High

710009

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

Small-scale

0.480

High

759083

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

759085

RT106
Histone chaperone RTT106

1

0

Small-scale

0.480

High

703618

PRS6A
26S proteasome regulatory subunit 6A

1

2

Small-scale

0.479

High

743537

HMT1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.479

High

759106

PUF3
mRNA-binding protein PUF3

1

9

Small-scale

0.479

High

759110

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

3

Small-scale

0.479

High

759107

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.460

High

375391

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

558058

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

662234

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

691998

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

756490

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

Small-scale

0.458

High

759088

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

Small-scale

0.458

High

759100

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

759105

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

754334

GIC1
GTPase-interacting component 1

1

1

High-throughput

0.457

High

759104

GIC2
GTPase-interacting component 2

1

1

High-throughput

0.457

High

366292

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

450049

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

491238

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

628055

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

633226

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

759084

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

759097

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

424524

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

556052

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

612231

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

759081

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

759089

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

759102

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

519940

TCPA
T-complex protein 1 subunit alpha

2

0

High-throughput

0.307

High

689788

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High

753620

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.282

High

757979

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.265

Low

423963

CBP1
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.249

Low

576142

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

746624

CDS1
Phosphatidate cytidylyltransferase

1

0

High-throughput

0.249

Low

759090

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low

746681

REG2
Protein REG2

1

0

High-throughput

0.238

Low

588081

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024