HitPredict

Interactor 1: ZFY16 (Q7Z3T8)
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)
Gene: ZFYVE16

Interactor 2: PTN23 (Q9H3S7)
Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)
Gene: PTPN23

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	34761192, 27880917, 28675297
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1539 Hs			1 1636
+	Hs
		1189511 ZFY16_HUMAN (1-1539): 0: 1705: 100.00		PDC6I_HUMAN (9-871): 7.58e-165: 523: 22.24
+	Hs
		313568 ZFYV9_HUMAN (141-1538): 0: 1128: 31.66		PTN23_HUMAN (1-1636): 0: 1052: 100.00
+	Hs
		160187 HGS_HUMAN (589-1090): 6.36e-77: 274: 16.08		PTN23_HUMAN (1-1636): 0: 1052: 100.00
+	Hs
		1067470 EEA1_HUMAN (124-805): 1.3e-55: 215: 12.94		PTN23_HUMAN (1-1636): 0: 1052: 100.00
+	Hs
		1260381 RUFY1_HUMAN (382-813): 5.4e-55: 207: 12.33		PDC6I_HUMAN (9-871): 7.58e-165: 523: 22.24
+	Dm
		1280452 HRS_DROME (710-852): 2.17e-30: 132: 26.90		Q9VUH6_DROME (254-1486): 4.08e-59: 227: 13.48
+	Hs
		640274 PKHF2_HUMAN (673-835): 8.01e-37: 141: 25.71		PTN3_HUMAN (1220-1457): 3.02e-34: 145: 36.78