Protein: LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)

Gene: LRCH1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9Y2L9

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0034260 - negative regulation of GTPase activity
GO:1990869 - cellular response to chemokine
GO:2000405 - negative regulation of T cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1294492

LRCH3
DISP complex protein LRCH3

3

20

High-throughput

0.871

High

1244090

DOCK8
Dedicator of cytokinesis protein 8

7

12

High-throughput

0.749

High

1298545

DOCK7
Dedicator of cytokinesis protein 7

6

12

High-throughput

0.672

High

910189

1433E
14-3-3 protein epsilon

3

10

High-throughput

0.650

High

1185507

MOB1B
MOB kinase activator 1B

2

5

High-throughput

0.621

High

264523

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

1

20

High-throughput

0.618

High

648641

CALL3
Calmodulin-like protein 3

1

20

High-throughput

0.618

High

1138594

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

19

High-throughput

0.618

High

1257268

LRC15
Leucine-rich repeat-containing protein 15

1

20

High-throughput

0.618

High

1172345

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

1333715

MOB1A
MOB kinase activator 1A

2

5

High-throughput

0.611

High

1357264

MYO6
Unconventional myosin-VI

2

6

High-throughput

0.611

High

1293670

DOCK6
Dedicator of cytokinesis protein 6

3

12

High-throughput

0.593

High

484224

CALM3
Calmodulin-3

1

20

High-throughput

0.575

High

1345966

TM14B
Transmembrane protein 14B

2

2

High-throughput

0.553

High

1377312

TM14A
Transmembrane protein 14A

2

2

High-throughput

0.553

High

385756

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

128935

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.536

High

535964

MIF
Macrophage migration inhibitory factor

1

2

High-throughput

0.536

High

927685

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

986873

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.536

High

1167788

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

20

High-throughput

0.536

High

1332799

EGLN3
Prolyl hydroxylase EGLN3

1

7

High-throughput

0.536

High

950335

SMAD3
Mothers against decapentaplegic homolog 3

1

12

Small-scale

0.515

High

484346

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

5

High-throughput

0.514

High

58852

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

305049

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.513

High

538631

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

707404

S10A3
Protein S100-A3

1

4

High-throughput

0.489

High

804382

NOTC1
Neurogenic locus notch homolog protein 1

1

5

High-throughput

0.489

High

976822

TAP2
Antigen peptide transporter 2

1

2

High-throughput

0.489

High

984685

CALD1
Caldesmon

1

3

High-throughput

0.489

High

1048827

TRI29
Tripartite motif-containing protein 29

1

5

High-throughput

0.489

High

1168272

CERS6
Ceramide synthase 6

1

2

High-throughput

0.489

High

1197782

DSG4
Desmoglein-4

1

5

High-throughput

0.489

High

1274558

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.489

High

1346177

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

2

High-throughput

0.489

High

1377311

SGT1
Protein SGT1 homolog

1

20

High-throughput

0.489

High

73195

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

20

High-throughput

0.479

High

163496

XPO1
Exportin-1

1

2

High-throughput

0.479

High

780353

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

894604

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

941599

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

1044294

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.479

High

1304191

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

1354919

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1356419

TNIK
TRAF2 and NCK-interacting protein kinase

1

11

High-throughput

0.457

High

262626

TULP3
Tubby-related protein 3

1

2

High-throughput

0.437

High

554097

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

652653

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

1066908

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

1269975

ESR2
Estrogen receptor beta

1

15

High-throughput

0.437

High

1343819

ANLN
Anillin

1

5

High-throughput

0.437

High

1028296

SBP1
Methanethiol oxidase

1

0

High-throughput

0.279

Low

1128592

CAHM4
Calcium homeostasis modulator protein 4

1

0

High-throughput

0.279

Low

1154402

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.279

Low

1197719

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

1346897

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.279

Low

1284403

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.249

Low

1131941

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024