HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26186194, 28514442, 31995728, 18024965
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 798
+	Hs
		121077 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403775 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403745 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		398159 LEG2_HUMAN (234-352): 1.96e-31: 117: 25.00		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		449183 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		556408 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		880584 LEG4_HUMAN (1-354): 6.2e-106: 315: 35.38		TEN4_HUMAN (356-480): 1.24e-09: 64.4: 9.22
+	Hs
		449369 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		50511 PPL13_HUMAN (221-353): 1.32e-31: 117: 25.00		A1L306_HUMAN (375-501): 6.8e-14: 78.2: 20.74
+	Hs
		1253493 PPL13_HUMAN (221-353): 1.32e-31: 117: 25.00		TENR_HUMAN (591-726): 1.07e-13: 77.4: 16.46
+	Hs
		449244 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26
+	Hs
		449220 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80