HitPredict

Interactor 1: RAI1 (Q7Z5J4)
Retinoic acid-induced protein 1
Gene: RAI1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1906 Hs			1 530
+	Hs
		377434 RAI1_HUMAN (1-1906): 0: 1594: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487554 RAI1_HUMAN (1-1906): 0: 1594: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1269850 TCF20_HUMAN (203-1903): 0: 645: 21.29		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377783 TCF20_HUMAN (203-1903): 0: 645: 21.29		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487817 TCF20_HUMAN (203-1903): 0: 645: 21.29		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		301151 KDM4B_HUMAN (1354-1903): 1.15e-62: 237: 13.31		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Mm
		587108 KDM4B_MOUSE (1411-1903): 8.66e-69: 256: 16.20		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Mm
		587107 KDM4C_MOUSE (1394-1903): 3.22e-68: 253: 11.58		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		301117 KDM4B_HUMAN (1354-1903): 1.15e-62: 237: 13.31		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		876710 BRPF1_HUMAN (1523-1902): 8.17e-47: 187: 12.17		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1219300 PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269924 KMT2B_HUMAN (1714-1905): 9.33e-38: 158: 22.80		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Mm
		587106 KDM4A_MOUSE (1398-1903): 8.11e-47: 186: 11.01		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		369955 PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370701 KMT2B_HUMAN (1714-1905): 9.33e-38: 158: 22.80		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369449 KMT2A_HUMAN (1715-1905): 1.1e-36: 155: 21.89		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782694 KMT2B_HUMAN (1714-1905): 9.33e-38: 158: 22.80		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377467 PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		580484 KDM4C_MOUSE (1394-1903): 3.22e-68: 253: 11.58		ANDR_MOUSE (149-407): 1.53e-38: 152: 33.70
+	Hs
		256937 KDM4A_HUMAN (1379-1903): 3.13e-47: 188: 13.21		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59