HitPredict

Interactor 1: RAI1 (Q7Z5J4)
Retinoic acid-induced protein 1
Gene: RAI1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0032922 - circadian regulation of gene expression GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1906 Hs			1 488
+	Hs
		1038492 RAI1_HUMAN (1-1906): 0: 1594: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1270502 TCF20_HUMAN (203-1903): 0: 645: 21.29		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038784 TCF20_HUMAN (203-1903): 0: 645: 21.29		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038707 KDM4C_HUMAN (1386-1906): 2.43e-70: 260: 13.42		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		975297 KMT2A_HUMAN (1715-1905): 1.1e-36: 155: 21.89		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		177381 KDM4C_HUMAN (1386-1906): 2.43e-70: 260: 13.42		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		256969 KDM4A_HUMAN (1379-1903): 3.13e-47: 188: 13.21		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038514 PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038822 KMT2B_HUMAN (1714-1905): 9.33e-38: 158: 22.80		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		975244 KMT2A_HUMAN (1715-1905): 1.1e-36: 155: 21.89		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177151 KDM4A_HUMAN (1379-1903): 3.13e-47: 188: 13.21		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1038652 MINT_HUMAN (395-1722): 4.02e-10: 67.5: 11.33		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		152639 KMT2D_HUMAN (1054-1821): 3.12e-09: 64.8: 11.73		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		319357 BRD1_HUMAN (1549-1902): 4.67e-43: 174: 12.02		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04