Protein: ARC1
tRNA-aminoacylation cofactor ARC1 (Acyl-RNA-complex protein 1) (GU4 nucleic-binding protein 1) (G4p1 protein) (P42) (tRNA-interacting factor ARC1)

Gene: ARC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 122
UniProt ID: P46672

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0005737 - cytoplasm
GO:0006418 - tRNA aminoacylation for protein translation
GO:0006424 - glutamyl-tRNA aminoacylation
GO:0006431 - methionyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

368908

SYMC
Methionine--tRNA ligase, cytoplasmic

12

11

Small-scale

0.981

High

858102

SYEC
Glutamate--tRNA ligase, cytoplasmic

11

7

Small-scale

0.757

High

392942

HSP82
ATP-dependent molecular chaperone HSP82

5

3

Small-scale

0.699

High

579624

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.584

High

858296

MCA1
Metacaspase-1

2

0

High-throughput

0.576

High

797971

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

795773

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

1

High-throughput

0.515

High

796095

IMB2
Importin subunit beta-2

1

0

High-throughput

0.513

High

858286

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

574703

KSS1
Mitogen-activated protein kinase KSS1

1

2

High-throughput

0.501

High

602533

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

648403

SYMM
Methionine--tRNA ligase, mitochondrial

1

11

Small-scale

0.501

High

656523

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

656806

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

748865

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.501

High

778909

NNK1
Nitrogen network kinase 1

1

1

High-throughput

0.501

High

808643

AURK
Aurora kinase

1

2

High-throughput

0.501

High

858272

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

4

High-throughput

0.501

High

858289

SKY1
Serine/threonine-protein kinase SKY1

1

5

High-throughput

0.501

High

858302

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.501

High

504679

YH41B
Transposon Ty4-H Gag-Pol polyprotein

1

0

High-throughput

0.493

High

557738

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.493

High

805773

YHT1
PH domain-containing protein YHR131C

1

0

High-throughput

0.493

High

811691

CAT8
Regulatory protein CAT8

1

0

High-throughput

0.493

High

858281

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.493

High

858299

RTK1
Probable serine/threonine-protein kinase RTK1

1

2

High-throughput

0.489

High

738036

MKK1
MAP kinase kinase MKK1/SSP32

1

3

High-throughput

0.481

High

441178

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

858285

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

646447

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.480

High

692386

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

758308

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.480

High

793169

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.480

High

801862

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.480

High

858273

BPL1
Biotin--protein ligase

1

0

Small-scale

0.480

High

858276

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

416257

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

435184

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

464613

PBS2
MAP kinase kinase PBS2

1

1

High-throughput

0.479

High

481900

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

7

Small-scale

0.479

High

514699

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

581878

SYKC
Lysine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

674697

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

687598

SYLC
Leucine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

709845

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

727136

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

737894

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

747442

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

783485

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

792115

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

802567

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

802649

YHI0
Putative proline--tRNA ligase YHR020W

1

4

High-throughput

0.479

High

858288

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

734138

EF2
Elongation factor 2

1

2

High-throughput

0.470

High

858294

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

2

High-throughput

0.470

High

149832

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

436034

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

558782

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

739401

ZUO1
Zuotin

1

0

High-throughput

0.458

High

778395

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

802244

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815093

SS120
Protein SSP120

1

0

High-throughput

0.458

High

815155

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

858274

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

858278

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

858279

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

858287

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

645948

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.457

High

808409

HAL5
Serine/threonine-protein kinase HAL5

1

2

High-throughput

0.457

High

819095

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

441986

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

504281

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

512511

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

679820

CDC48
Cell division control protein 48

1

1

High-throughput

0.437

High

682323

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

858298

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

798058

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

3

High-throughput

0.407

High

758010

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

811624

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

449289

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.279

Low

672253

CDC10
Cell division control protein 10

1

0

High-throughput

0.279

Low

762979

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.279

Low

858291

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

693197

PHO91
Low-affinity phosphate transporter PHO91

1

0

High-throughput

0.269

Low

743584

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.269

Low

776756

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.269

Low

797182

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.269

Low

798744

PHO89
Phosphate permease PHO89

1

0

High-throughput

0.269

Low

808747

ATU2
Copper-transporting ATPase

1

0

High-throughput

0.269

Low

818563

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.269

Low

827038

MGA2
Protein MGA2

1

0

High-throughput

0.269

Low

858283

HDA1
Histone deacetylase HDA1

1

0

High-throughput

0.269

Low

858304

NAH1

1

0

High-throughput

0.269

Low

858277

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

826022

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.251

Low

383769

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410203

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433710

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

455130

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503115

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

513083

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

670865

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

689530

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

707458

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

753444

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

808846

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

812429

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

826610

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

849640

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

858275

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

858280

H1
Histone H1

1

0

High-throughput

0.249

Low

858282

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

858284

H3
Histone H3

1

0

High-throughput

0.249

Low

858290

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

858292

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

858293

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

858295

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

858297

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

858300

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

858301

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

858303

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

807237

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025