HitPredict

Interactor 1: RBBP6 (Q7Z6E9)
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)
Gene: RBBP6

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1792 Hs			1 357
+	Hs
		1191731 RBBP6_HUMAN (1-1792): 1.97e-152: 516: 100.00		NLE1_HUMAN (2-312): 5.34e-81: 256: 21.45
+	Hs
		1146565 RBBP6_HUMAN (1-1792): 1.97e-152: 516: 100.00		A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87
+	Mm
		957036 RBBP6_MOUSE (1-1752): 5.63e-145: 494: 88.54		A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56
+	Hs
		1302927 MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98		NLE1_HUMAN (2-312): 5.34e-81: 256: 21.45
+	Hs
		903375 BD1L1_HUMAN (851-1782): 4.77e-20: 100: 13.46		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		903374 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		903393 ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		1288258 MINT_HUMAN (76-1784): 4.28e-28: 126: 7.98		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		1056932 MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Sc
		630897 MDN1_YEAST (1033-1533): 2.04e-15: 84.9: 15.37		NLE1_YEAST (92-355): 1.07e-65: 217: 22.29
+	Hs
		1264567 ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		1264784 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		230410 ZC3H1_HUMAN (679-1650): 2.57e-10: 68: 12.68		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		1146674 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87
+	Mm
		1111991 PRC2C_MOUSE (378-1509): 7.48e-16: 86.5: 8.74		A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56
+	Hs
		1281391 PRR36_HUMAN (50-1049): 1.75e-21: 104: 10.55		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		1147005 PRC2C_HUMAN (87-1452): 1.6e-12: 75.4: 8.27		A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87
+	Dm
		1370295 Q9VLS7_DROME (382-1689): 4.6e-21: 103: 7.43		POC1_DROME (4-149): 4.96e-26: 108: 18.49