HitPredict

Interactor 1: RBBP6 (Q7Z6E9)
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)
Gene: RBBP6

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32460013
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016607 - nuclear speck
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1792 Hs			1 2752
+	Hs
		807793 PRG4_HUMAN (40-917): 5.82e-20: 99.5: 10.05		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		807690 ANK2_HUMAN (331-1734): 6.96e-13: 76.5: 11.90		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Dm
		1187396 Q9VLS7_DROME (382-1689): 4.6e-21: 103: 7.43		Q7YZ99_DROME (1-876): 3.94e-54: 210: 21.48
+	Dm
		54892 Q9VLS7_DROME (382-1689): 4.6e-21: 103: 7.43		A1ZA72_DROME (79-1899): 3.07e-34: 148: 10.30
+	Hs
		1056897 MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Dm
		1376672 FUTSC_DROME (371-1792): 9.87e-21: 102: 11.61		FUTSC_DROME (149-2601): 1.34e-21: 106: 12.75
+	Dm
		113976 M9PB30_DROME (259-1062): 5.51e-26: 120: 9.10		M9PB30_DROME (2292-2752): 2.57e-14: 82: 11.45
+	Dm
		1214590 Q9VLS7_DROME (382-1689): 4.6e-21: 103: 7.43		Q8IQA6_DROME (20-1572): 3.87e-17: 91.3: 7.81
+	Hs
		1264771 TITIN_HUMAN (79-1153): 3.14e-15: 84.6: 10.07		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Dm
		1182373 Q9VLS7_DROME (382-1689): 4.6e-21: 103: 7.43		Q7KU92_DROME (1486-2593): 1.59e-09: 66.4: 11.55
+	Dm
		65570 FUTSC_DROME (371-1792): 9.87e-21: 102: 11.61		A8JNM5_DROME (1486-2593): 8.81e-10: 67.1: 11.55
+	Hs
		1243827 BD1L1_HUMAN (851-1782): 4.77e-20: 100: 13.46		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152668 BD1L1_HUMAN (851-1782): 4.77e-20: 100: 13.46		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Mm
		1351630 PCLO_MOUSE (276-1782): 2.57e-09: 65: 8.17		PCLO_MOUSE (8-2704): 3.33e-19: 98.2: 7.94
+	Hs
		1154038 NIPBL_HUMAN (880-1382): 5.38e-11: 70.3: 18.50		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		821099 PRC2C_HUMAN (87-1452): 1.6e-12: 75.4: 8.27		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		152667 KMT2C_HUMAN (88-1775): 2.2e-16: 88.1: 7.78		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75