HitPredict

Interactor 1: HUWE1 (Q7Z6Z7)
E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)
Gene: HUWE1

Interactor 2: ARF (Q8N726)
Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p14ARF)
Gene: CDKN2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	26496610, 15989956
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion and 1 others more... GO:0005829 - cytosol
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 4374 Hs			1 132
+	Mm
		1145384 HUWE1_MOUSE (1-4374): 0: 3203: 96.37		ARF_MOUSE (1-128): 3.31e-40: 133: 49.22