Protein: DNJB8
DnaJ homolog subfamily B member 8

Gene: DNJB8, DNAJB8
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q8NHS0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030544 - Hsp70 protein binding
GO:0044183 - protein folding chaperone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679376

DNJB2
DnaJ homolog subfamily B member 2

3

16

High-throughput

0.861

High

537555

HSP7C
Heat shock cognate 71 kDa protein

2

20

High-throughput

0.789

High

274671

DNJB6
DnaJ homolog subfamily B member 6

2

16

High-throughput

0.776

High

761455

HS71L
Heat shock 70 kDa protein 1-like

2

20

High-throughput

0.737

High

946171

MLF1
Myeloid leukemia factor 1

4

13

High-throughput

0.691

High

1340515

THAP2
THAP domain-containing protein 2

3

1

High-throughput

0.667

High

1209414

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.665

High

1340509

DNJC7
DnaJ homolog subfamily C member 7

1

20

High-throughput

0.665

High

1340497

ESS2
Splicing factor ESS-2 homolog

3

0

High-throughput

0.638

High

342969

HERC2
E3 ubiquitin-protein ligase HERC2

1

10

High-throughput

0.618

High

600870

HSP76
Heat shock 70 kDa protein 6

1

20

Small-scale

0.618

High

679214

DNJB1
DnaJ homolog subfamily B member 1

1

16

High-throughput

0.618

High

761775

HSP74
Heat shock 70 kDa protein 4

1

20

High-throughput

0.618

High

801421

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.618

High

931009

HSP72
Heat shock-related 70 kDa protein 2

1

20

High-throughput

0.618

High

1340523

DJB12
DnaJ homolog subfamily B member 12

1

19

High-throughput

0.618

High

1340519

ZBT20
Zinc finger and BTB domain-containing protein 20

2

6

High-throughput

0.601

High

723944

LCN1
Lipocalin-1

2

1

High-throughput

0.574

High

1340528

CHIP
E3 ubiquitin-protein ligase CHIP

2

20

High-throughput

0.571

High

338913

CBX6
Chromobox protein homolog 6

1

3

High-throughput

0.536

High

896420

ERF
ETS domain-containing transcription factor ERF

1

3

High-throughput

0.536

High

1121468

KEAP1
Kelch-like ECH-associated protein 1

1

12

High-throughput

0.536

High

1253909

FA83H
Protein FAM83H

1

1

High-throughput

0.536

High

1257924

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

8

High-throughput

0.536

High

1316841

ASPM
Abnormal spindle-like microcephaly-associated protein

1

5

High-throughput

0.536

High

1340495

NACC2
Nucleus accumbens-associated protein 2

1

11

High-throughput

0.536

High

1340510

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

1

High-throughput

0.536

High

1340513

IDI2
Isopentenyl-diphosphate delta-isomerase 2

1

0

High-throughput

0.513

High

1129294

BLTP2
Bridge-like lipid transfer protein family member 2

1

1

High-throughput

0.489

High

1219855

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.489

High

1275911

MAMC2
MAM domain-containing protein 2

1

2

High-throughput

0.489

High

229048

AKAP8
A-kinase anchor protein 8

1

1

High-throughput

0.479

High

294055

CD123
Translation initiation factor eIF2 assembly protein

1

7

High-throughput

0.479

High

343267

ERR2
Steroid hormone receptor ERR2

1

17

High-throughput

0.479

High

347191

BAG2
BAG family molecular chaperone regulator 2

1

12

High-throughput

0.479

High

348622

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.479

High

731479

STIP1
Stress-induced-phosphoprotein 1

1

20

High-throughput

0.479

High

854891

RECQ1
ATP-dependent DNA helicase Q1

1

6

High-throughput

0.479

High

880343

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.479

High

894917

EMD
Emerin

1

3

High-throughput

0.479

High

941022

HDAC4
Histone deacetylase 4

1

13

Small-scale

0.479

High

1092704

AF1Q
Protein AF1q

1

1

High-throughput

0.479

High

1106008

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

20

High-throughput

0.479

High

1125558

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

20

High-throughput

0.479

High

1126480

CAPR1
Caprin-1

1

7

High-throughput

0.479

High

1163485

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.479

High

1211320

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

3

High-throughput

0.479

High

1312352

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

4

Small-scale

0.479

High

1340499

SEH1
Nucleoporin SEH1

1

8

High-throughput

0.479

High

1340506

CK5P2
CDK5 regulatory subunit-associated protein 2

1

10

High-throughput

0.479

High

1340511

TBA1C
Tubulin alpha-1C chain

1

17

High-throughput

0.479

High

1340512

TBB6
Tubulin beta-6 chain

1

16

High-throughput

0.479

High

1340516

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

7

High-throughput

0.479

High

1340517

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

1340518

GRPE1
GrpE protein homolog 1, mitochondrial

1

9

High-throughput

0.479

High

1340521

GEMI8
Gem-associated protein 8

1

1

High-throughput

0.479

High

1340522

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.479

High

1340524

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

1

High-throughput

0.479

High

1340525

HDAC6
Protein deacetylase HDAC6

1

13

Small-scale

0.479

High

1340526

BAG5
BAG family molecular chaperone regulator 5

1

18

High-throughput

0.479

High

1340529

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

1

High-throughput

0.479

High

1340530

SGT1
Protein SGT1 homolog

1

11

High-throughput

0.479

High

1340508

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.458

High

410952

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

17

High-throughput

0.445

High

442766

RB
Retinoblastoma-associated protein

1

1

High-throughput

0.445

High

547174

PYC
Pyruvate carboxylase, mitochondrial

1

6

High-throughput

0.445

High

1029877

RUNX1
Runt-related transcription factor 1

1

3

High-throughput

0.445

High

1047234

ATP7A
Copper-transporting ATPase 1

1

3

High-throughput

0.445

High

1149448

SKI2
Superkiller complex protein 2

1

7

High-throughput

0.445

High

1200920

WDR81
WD repeat-containing protein 81

1

11

High-throughput

0.445

High

1219692

CARL1
F-actin-uncapping protein LRRC16A

1

5

High-throughput

0.445

High

1244356

SKI3
Superkiller complex protein 3

1

18

High-throughput

0.445

High

1278511

TT21B
Tetratricopeptide repeat protein 21B

1

14

High-throughput

0.445

High

1289009

NLRX1
NLR family member X1

1

6

High-throughput

0.445

High

1316749

WDFY3
WD repeat and FYVE domain-containing protein 3

1

13

High-throughput

0.445

High

1323303

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

2

High-throughput

0.445

High

1323799

ARG28
Rho guanine nucleotide exchange factor 28

1

3

High-throughput

0.445

High

1340496

DOC10
Dedicator of cytokinesis protein 10

1

1

High-throughput

0.445

High

1340503

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

6

High-throughput

0.445

High

1340504

GCP5
Gamma-tubulin complex component 5

1

2

High-throughput

0.445

High

1340520

PANK4
4'-phosphopantetheine phosphatase

1

1

High-throughput

0.445

High

1340531

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

4

High-throughput

0.445

High

124409

HAX1
HCLS1-associated protein X-1

1

3

High-throughput

0.437

High

228840

SCO2
Protein SCO2 homolog, mitochondrial

1

4

High-throughput

0.437

High

353960

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

1

High-throughput

0.437

High

520933

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

3

High-throughput

0.437

High

1162194

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

1

High-throughput

0.437

High

1192063

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

3

High-throughput

0.437

High

1195668

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

4

High-throughput

0.437

High

1340492

TM263
Transmembrane protein 263

1

1

High-throughput

0.437

High

1340493

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.437

High

1340500

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

1

High-throughput

0.437

High

1340507

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

3

High-throughput

0.437

High

1081187

ELP6
Elongator complex protein 6

1

0

High-throughput

0.426

High

1224753

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.426

High

1322262

FCSK
L-fucose kinase

1

0

High-throughput

0.426

High

1340490

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.426

High

1340494

FERM2
Fermitin family homolog 2

1

0

High-throughput

0.426

High

1340498

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.426

High

1340501

INT4
Integrator complex subunit 4

1

0

High-throughput

0.426

High

753829

MRP1
Multidrug resistance-associated protein 1

1

2

High-throughput

0.407

High

1119514

PEBB
Core-binding factor subunit beta

1

1

High-throughput

0.407

High

1228877

ZFY26
Zinc finger FYVE domain-containing protein 26

1

4

High-throughput

0.407

High

1331310

S2529
Mitochondrial basic amino acids transporter

1

6

High-throughput

0.407

High

1340491

TB22A
TBC1 domain family member 22A

1

4

High-throughput

0.407

High

1340502

KIRR1
Kin of IRRE-like protein 1

1

2

High-throughput

0.407

High

1340505

IF140
Intraflagellar transport protein 140 homolog

1

5

High-throughput

0.407

High

286571

SG2A1
Mammaglobin-B

3

0

High-throughput

0.347

High

1312843

CI040
Uncharacterized protein C9orf40

3

0

High-throughput

0.347

High

48162

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.249

Low

789930

FDFT
Squalene synthase

1

0

High-throughput

0.249

Low

361707

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.232

Low

1340514

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.232

Low

1340527

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025