Protein: IGHM
Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)

Gene: IGHM
Organism: Homo sapiens
Interactions: 136
UniProt ID: P01871

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002331 - pre-B cell allelic exclusion
GO:0003823 - antigen binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

353180

KVD40
Immunoglobulin kappa variable 2D-40

1

16

High-throughput

0.575

High

353204

LV147
Immunoglobulin lambda variable 1-47

1

20

High-throughput

0.575

High

353482

IGKC
Immunoglobulin kappa constant

1

16

High-throughput

0.575

High

353903

FINC
Fibronectin

1

14

High-throughput

0.575

High

353972

FNDC5
Fibronectin type III domain-containing protein 5

1

5

High-throughput

0.575

High

353911

1433T
14-3-3 protein theta

2

8

High-throughput

0.552

High

126327

MATN2
Matrilin-2

1

9

High-throughput

0.514

High

198341

KLK10
Kallikrein-10

1

8

High-throughput

0.514

High

353982

SNX27
Sorting nexin-27

2

12

High-throughput

0.504

High

353995

DDX31
ATP-dependent DNA helicase DDX31

2

8

High-throughput

0.504

High

353915

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.457

High

353988

SH3G2
Endophilin-A1

1

8

High-throughput

0.457

High

161489

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

183001

P2RX6
P2X purinoceptor 6

1

4

High-throughput

0.445

High

239690

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

295785

ST17B
Serine/threonine-protein kinase 17B

1

8

High-throughput

0.445

High

328083

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.445

High

353902

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.445

High

353905

K2C1
Keratin, type II cytoskeletal 1

1

7

High-throughput

0.445

High

353906

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.445

High

353909

AATC
Aspartate aminotransferase, cytoplasmic

1

6

High-throughput

0.445

High

353912

CCR1
C-C chemokine receptor type 1

1

11

High-throughput

0.445

High

353913

K1C9
Keratin, type I cytoskeletal 9

1

12

High-throughput

0.445

High

353918

STX17
Syntaxin-17

1

3

High-throughput

0.445

High

353920

TBA4A
Tubulin alpha-4A chain

1

5

High-throughput

0.445

High

353921

HBB
Hemoglobin subunit beta

1

5

High-throughput

0.445

High

353922

PRAME
Melanoma antigen preferentially expressed in tumors

1

1

High-throughput

0.445

High

353925

TAP1
Antigen peptide transporter 1

1

1

High-throughput

0.445

High

353927

BTK
Tyrosine-protein kinase BTK

1

10

Small-scale

0.445

High

353928

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.445

High

353930

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

6

High-throughput

0.445

High

353933

PAPP1
Pappalysin-1

1

5

High-throughput

0.445

High

353934

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.445

High

353935

TBB3
Tubulin beta-3 chain

1

5

High-throughput

0.445

High

353955

CSPG4
Chondroitin sulfate proteoglycan 4

1

6

High-throughput

0.445

High

353958

TBA1A
Tubulin alpha-1A chain

1

5

High-throughput

0.445

High

353969

ABD12
Lysophosphatidylserine lipase ABHD12

1

1

High-throughput

0.445

High

353973

AT11C
Phospholipid-transporting ATPase IG

1

2

High-throughput

0.445

High

353975

OR5H6
Olfactory receptor 5H6

1

2

High-throughput

0.445

High

353987

EGFL8
Epidermal growth factor-like protein 8

1

18

High-throughput

0.445

High

354005

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

6

High-throughput

0.445

High

354009

S27A6
Long-chain fatty acid transport protein 6

1

1

High-throughput

0.445

High

48222

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.426

High

155706

APOL1
Apolipoprotein L1

1

0

High-throughput

0.426

High

168224

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.426

High

234759

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.426

High

344609

CO3
Complement C3

1

0

High-throughput

0.426

High

353907

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.426

High

353908

CD19
B-lymphocyte antigen CD19

1

0

Small-scale

0.426

High

353926

ATP7A
Copper-transporting ATPase 1

1

0

High-throughput

0.426

High

353974

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.426

High

353978

SYMPK
Symplekin

1

0

High-throughput

0.426

High

353990

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

353991

ABHD6
Monoacylglycerol lipase ABHD6

1

0

High-throughput

0.426

High

353998

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.426

High

354011

DOP2
Protein dopey-2

1

0

High-throughput

0.426

High

353904

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.417

High

353940

MAPK3
MAP kinase-activated protein kinase 3

1

2

High-throughput

0.417

High

354000

UBQL4
Ubiquilin-4

1

8

High-throughput

0.417

High

354002

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.417

High

64477

GOG8A
Golgin subfamily A member 8A

1

6

High-throughput

0.407

High

157274

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

2

High-throughput

0.407

High

203083

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

1

High-throughput

0.407

High

214745

PM34
Peroxisomal membrane protein PMP34

1

5

High-throughput

0.407

High

303622

OR2A4
Olfactory receptor 2A4

1

6

High-throughput

0.407

High

312693

CXB5
Gap junction beta-5 protein

1

7

High-throughput

0.407

High

326967

ABHGA
Phosphatidylserine lipase ABHD16A

1

1

High-throughput

0.407

High

353914

MTOR
Serine/threonine-protein kinase mTOR

1

4

High-throughput

0.407

High

353917

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

4

High-throughput

0.407

High

353919

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

3

High-throughput

0.407

High

353923

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.407

High

353924

RUNX1
Runt-related transcription factor 1

1

3

High-throughput

0.407

High

353929

SRBP2
Sterol regulatory element-binding protein 2

1

3

High-throughput

0.407

High

353931

STK4
Serine/threonine-protein kinase 4

1

9

High-throughput

0.407

High

353932

STK3
Serine/threonine-protein kinase 3

1

8

High-throughput

0.407

High

353937

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.407

High

353938

UBE3C
Ubiquitin-protein ligase E3C

1

4

High-throughput

0.407

High

353943

T176B
Transmembrane protein 176B

1

3

High-throughput

0.407

High

353946

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

2

High-throughput

0.407

High

353947

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

9

High-throughput

0.407

High

353949

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

9

High-throughput

0.407

High

353951

ACD10
Acyl-CoA dehydrogenase family member 10

1

1

High-throughput

0.407

High

353952

SFXN4
Sideroflexin-4

1

5

High-throughput

0.407

High

353954

CTR9
RNA polymerase-associated protein CTR9 homolog

1

5

High-throughput

0.407

High

353956

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

4

High-throughput

0.407

High

353959

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.407

High

353963

CIR1
Corepressor interacting with RBPJ 1

1

6

High-throughput

0.407

High

353964

MICU3
Calcium uptake protein 3, mitochondrial

1

1

High-throughput

0.407

High

353965

CERS3
Ceramide synthase 3

1

6

High-throughput

0.407

High

353966

SLX4
Structure-specific endonuclease subunit SLX4

1

5

High-throughput

0.407

High

353967

ELOA2
Elongin-A2

1

5

High-throughput

0.407

High

353970

KTAP2
Keratinocyte-associated protein 2

1

1

High-throughput

0.407

High

353976

RHBL4
Rhomboid-related protein 4

1

7

High-throughput

0.407

High

353977

GCN1
Stalled ribosome sensor GCN1

1

1

High-throughput

0.407

High

353980

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.407

High

353984

CP2S1
Cytochrome P450 2S1

1

3

High-throughput

0.407

High

353985

ARI3A
AT-rich interactive domain-containing protein 3A

1

1

Small-scale

0.407

High

353986

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.407

High

353989

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.407

High

353993

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.407

High

353994

SAV1
Protein salvador homolog 1

1

7

High-throughput

0.407

High

353996

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.407

High

353997

COE2
Transcription factor COE2

1

5

High-throughput

0.407

High

353999

MBNL1
Muscleblind-like protein 1

1

3

High-throughput

0.407

High

354001

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

9

High-throughput

0.407

High

354003

BAZ1B
Tyrosine-protein kinase BAZ1B

1

2

High-throughput

0.407

High

354004

PHF11
PHD finger protein 11

1

11

High-throughput

0.407

High

354006

FBX2
F-box only protein 2

1

4

High-throughput

0.407

High

354007

TSN16
Tetraspanin-16

1

7

High-throughput

0.407

High

354008

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

2

High-throughput

0.407

High

353961

PATL1
Protein PAT1 homolog 1

2

0

High-throughput

0.288

High

353910

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.238

Low

353939

SMN
Survival motor neuron protein

1

0

High-throughput

0.238

Low

353979

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.238

Low

176524

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.232

Low

245866

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.232

Low

296846

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.232

Low

353916

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.232

Low

353936

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.232

Low

353941

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.232

Low

353942

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

0

High-throughput

0.232

Low

353944

SPDE7
Putative speedy protein E7

1

0

High-throughput

0.232

Low

353945

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.232

Low

353948

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.232

Low

353950

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.232

Low

353953

GOLM2
Protein GOLM2

1

0

High-throughput

0.232

Low

353957

ZN574
Zinc finger protein 574

1

0

High-throughput

0.232

Low

353960

VP13B
Intermembrane lipid transfer protein VPS13B

1

0

High-throughput

0.232

Low

353962

ADCK1
AarF domain-containing protein kinase 1

1

0

High-throughput

0.232

Low

353968

GHDC
GH3 domain-containing protein

1

0

High-throughput

0.232

Low

353971

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

0

High-throughput

0.232

Low

353981

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.232

Low

353983

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

0

High-throughput

0.232

Low

353992

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.232

Low

354010

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.232

Low

354012

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024