Protein: CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)

Gene: CTDS2, CTDSP2
Organism: Homo sapiens
Interactions: 65
UniProt ID: O14595

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0006470 - protein dephosphorylation
GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0046872 - metal ion binding
GO:2000134 - negative regulation of G1/S transition of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158591

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

3

7

High-throughput

0.861

High

158536

CTDSL
CTD small phosphatase-like protein

1

7

High-throughput

0.691

High

158573

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

7

High-throughput

0.691

High

158586

CDCA3
Cell division cycle-associated protein 3

9

3

High-throughput

0.690

High

158549

UBF1
Nucleolar transcription factor 1

3

3

High-throughput

0.667

High

158569

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

3

High-throughput

0.667

High

158593

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

2

High-throughput

0.667

High

158595

INT6
Integrator complex subunit 6

3

2

High-throughput

0.667

High

158539

ENDD1
Endonuclease domain-containing 1 protein

3

0

High-throughput

0.638

High

158583

P121A
Nuclear envelope pore membrane protein POM 121

3

0

High-throughput

0.638

High

158590

PRR14
Proline-rich protein 14

3

0

High-throughput

0.638

High

158579

AN13A
Ankyrin repeat domain-containing protein 13A

4

5

High-throughput

0.630

High

158538

TBCD4
TBC1 domain family member 4

3

2

High-throughput

0.609

High

158570

MA7D1
MAP7 domain-containing protein 1

3

5

High-throughput

0.609

High

158574

AN13D
Ankyrin repeat domain-containing protein 13D

2

6

High-throughput

0.574

High

158560

NEK4
Serine/threonine-protein kinase Nek4

2

8

High-throughput

0.558

High

158567

MAP7
Ensconsin

2

4

High-throughput

0.558

High

158577

PKHH3
Pleckstrin homology domain-containing family H member 3

2

1

High-throughput

0.558

High

158535

N4BP3
NEDD4-binding protein 3

2

3

High-throughput

0.553

High

158564

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.553

High

158544

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

6

High-throughput

0.541

High

158553

EPHA3
Ephrin type-A receptor 3

1

7

High-throughput

0.541

High

158572

TBB8
Tubulin beta-8 chain

1

4

High-throughput

0.536

High

158575

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.536

High

158584

NEK1
Serine/threonine-protein kinase Nek1

1

9

High-throughput

0.536

High

158589

TBB6
Tubulin beta-6 chain

1

4

High-throughput

0.536

High

158545

ANDR
Androgen receptor

1

1

Small-scale

0.529

High

158552

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

7

Small-scale

0.501

High

158548

INSRR
Insulin receptor-related protein

1

6

High-throughput

0.494

High

158551

EPHA1
Ephrin type-A receptor 1

1

6

High-throughput

0.494

High

158565

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

12

High-throughput

0.494

High

158566

PTK7
Inactive tyrosine-protein kinase 7

1

5

High-throughput

0.494

High

124137

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.489

High

158543

MBP
Myelin basic protein

1

2

High-throughput

0.489

High

158546

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.489

High

158547

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.489

High

158555

BASI
Basigin

1

2

High-throughput

0.489

High

158558

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

2

High-throughput

0.489

High

158582

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.489

High

158554

AKT1
RAC-alpha serine/threonine-protein kinase

1

4

High-throughput

0.481

High

158541

SNAI1
Zinc finger protein SNAI1

1

15

Small-scale

0.479

High

158556

ARL3
ADP-ribosylation factor-like protein 3

1

3

High-throughput

0.479

High

158557

ARL1
ADP-ribosylation factor-like protein 1

1

2

High-throughput

0.479

High

158561

AT12A
Potassium-transporting ATPase alpha chain 2

1

3

High-throughput

0.479

High

158568

SMAD1
Mothers against decapentaplegic homolog 1

1

6

Small-scale

0.479

High

158587

GPA33
Cell surface A33 antigen

1

2

High-throughput

0.470

High

158534

SET1A
Histone-lysine N-methyltransferase SETD1A

1

0

High-throughput

0.458

High

158542

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.457

High

158537

MCAT
Mitochondrial carnitine/acylcarnitine carrier protein

1

4

High-throughput

0.437

High

158562

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.437

High

158563

ARF3
ADP-ribosylation factor 3

1

1

High-throughput

0.437

High

158571

AR13B
ADP-ribosylation factor-like protein 13B

1

5

High-throughput

0.437

High

158580

ARL14
ADP-ribosylation factor-like protein 14

1

2

High-throughput

0.437

High

158581

ARL8A
ADP-ribosylation factor-like protein 8A

1

2

High-throughput

0.437

High

158592

UBP29
Ubiquitin carboxyl-terminal hydrolase 29

1

4

Small-scale

0.437

High

158594

ARL15
ADP-ribosylation factor-like protein 15

1

2

High-throughput

0.437

High

158596

ARL5A
ADP-ribosylation factor-like protein 5A

1

3

High-throughput

0.437

High

158585

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.407

High

158588

MIC25
MICOS complex subunit MIC25

1

1

High-throughput

0.407

High

158540

ZMYM6
Zinc finger MYM-type protein 6

3

0

High-throughput

0.347

High

158578

ZC3H3
Zinc finger CCCH domain-containing protein 3

3

0

High-throughput

0.347

High

158576

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.279

Low

158559

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

158550

ANPRB
Atrial natriuretic peptide receptor 2

1

0

High-throughput

0.232

Low

158597

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025