HitPredict

Interactor 1: PKHH3 (Q7Z736)
Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3)
Gene: PLEKHH3

Interactor 2: SKAP1 (Q86WV1)
Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)
Gene: SKAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~RA
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 359
+	Bt
		945191 MYO10_BOVIN (87-757): 0: 663: 38.38		MYO10_BOVIN (108-245): 1.64e-33: 133: 23.45
+	Hs
		1336718 MYO10_HUMAN (87-768): 0: 658: 37.34		MYO10_HUMAN (108-245): 2.15e-32: 130: 23.45
+	Hs
		1331713 TLN1_HUMAN (401-786): 1.57e-75: 270: 13.56		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1224663 TLN1_HUMAN (401-786): 1.57e-75: 270: 13.56		ABI1_HUMAN (288-358): 6.21e-21: 95.6: 26.76
+	Hs
		1263849 RHG39_HUMAN (218-421): 3.48e-37: 152: 17.13		CNKR2_HUMAN (56-301): 1.55e-37: 145: 17.72
+	Hs
		505681 EPB41_HUMAN (360-788): 2.75e-48: 186: 11.74		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Mm
		886883 RHG39_MOUSE (233-421): 1.14e-34: 144: 15.09		CNKR2_MOUSE (56-301): 2.1e-37: 145: 17.72
+	Hs
		1319367 RHG39_HUMAN (218-421): 3.48e-37: 152: 17.13		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1295652 MY15B_HUMAN (205-482): 1.04e-17: 90.8: 19.16		ABI2_HUMAN (285-358): 1.02e-23: 103: 29.73