HitPredict

Interactor 1: Q7ZVZ9 (Q7ZVZ9)
Suppressor of fused homolog
Gene: sufu

Interactor 2: Q800Z9 (Q800Z9)
Zinc finger transcription factor detour
Gene: gli1

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24339784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007224 - smoothened signaling pathway GO:0035301 - Hedgehog signaling complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 485 Dr			1 1404
+	Dr
		1193346 Q7ZVZ9_DANRE (1-485): 0: 898: 100.00		Q9YGS4_DANRE (1-1404): 0: 670: 36.53
+	Mm
		1142949 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI3_MOUSE (1-1403): 0: 722: 32.82
+	Hs
		485150 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI3_HUMAN (1-1403): 0: 712: 32.09
+	Hs
		485095 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI2_HUMAN (1-1404): 0: 647: 33.55
+	Mm
		814025 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI1_MOUSE (54-1401): 0: 607: 35.48
+	Hs
		436760 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI1_HUMAN (63-1401): 0: 589: 36.64
+	Mm
		1012691 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI2_MOUSE (1-1404): 8.33e-161: 526: 34.79
+	Hs
		1243032 SUFU_HUMAN (1-485): 0: 825: 78.92		GLIS3_HUMAN (304-512): 1.24e-52: 201: 55.71
+	Hs
		1080643 SUFU_HUMAN (1-485): 0: 825: 78.92		ZIC1_HUMAN (307-451): 1.49e-41: 161: 54.80
+	Dm
		585801 Q9VG38_DROME (21-485): 0: 688: 36.27		CI_DROME (293-466): 3.06e-76: 280: 79.89
+	Dm
		585716 Q27279_DROME (21-485): 0: 681: 36.07		CI_DROME (293-466): 3.06e-76: 280: 79.89