HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: GRID2 (Q61625)
Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)
Gene: GRID2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15207857
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043197 - dendritic spine GO:0097110 - scaffold protein binding GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 1007
+	Mm
		771471 SHAN3_MOUSE (1-1730): 0: 649: 100.00		NMDZ1_MOUSE (7-913): 0: 636: 22.23
+	Mm
		1223156 SHAN2_MOUSE (356-1727): 3.12e-100: 357: 35.35		GRID2_MOUSE (1-1007): 0: 919: 100.00
+	Mm
		1029194 SHAN3_MOUSE (1-1730): 0: 649: 100.00		NMDE2_MOUSE (2-967): 0: 570: 19.37
+	Mm
		92679 SHAN1_MOUSE (371-1725): 5.8e-29: 129: 13.19		GRID2_MOUSE (1-1007): 0: 919: 100.00
+	Rn
		623733 SHAN2_RAT (356-1727): 1.4e-98: 352: 35.53		GRIA4_RAT (10-865): 0: 691: 25.34
+	Mm
		771490 SHAN2_MOUSE (356-1727): 3.12e-100: 357: 35.35		NMDZ1_MOUSE (7-913): 0: 636: 22.23
+	Mm
		1029221 SHAN2_MOUSE (356-1727): 3.12e-100: 357: 35.35		NMDE2_MOUSE (2-967): 0: 570: 19.37
+	Hs
		1051674 ANKK1_HUMAN (181-542): 9.07e-64: 235: 19.34		NMDZ1_HUMAN (7-913): 0: 635: 22.34
+	Mm
		771489 DAPK1_MOUSE (2-202): 8.93e-38: 157: 17.16		NMDZ1_MOUSE (7-913): 0: 636: 22.23
+	Rn
		771531 SHAN1_RAT (371-1725): 8.77e-29: 128: 12.44		NMDZ1_RAT (7-913): 0: 636: 22.34
+	Mm
		1029220 DAPK1_MOUSE (2-202): 8.93e-38: 157: 17.16		NMDE2_MOUSE (2-967): 0: 570: 19.37
+	Rn
		1028071 SHAN1_RAT (371-1725): 8.77e-29: 128: 12.44		NMDE2_RAT (2-967): 0: 573: 19.18