HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: PELP1 (Q9DBD5)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor)
Gene: PELP1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21589869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 305 Mm			1 1123
+	Mm
		101829 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		F8WI37_MOUSE (472-1086): 1.02e-14: 82: 12.37
+	Mm
		1194614 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		KMT2C_MOUSE (472-1086): 9.94e-15: 82: 12.37
+	Hs
		620215 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		679182 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Mm
		57190 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		CHD7_MOUSE (479-1011): 5.64e-10: 66.2: 11.68
+	Hs
		839836 LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		641583 PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		822688 LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		799152 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		213398 TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		201848 HXA2_HUMAN (2-305): 3.15e-40: 145: 18.93		SYNJ1_HUMAN (493-887): 8.09e-09: 62.3: 10.70
+	Hs
		658629 MSX1_HUMAN (4-185): 2.74e-36: 133: 29.19		CBP_HUMAN (643-1093): 3.52e-12: 73.4: 13.66
+	Hs
		620186 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		CBP_HUMAN (643-1093): 3.52e-12: 73.4: 13.66
+	Hs
		679149 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		CBP_HUMAN (643-1093): 3.52e-12: 73.4: 13.66
+	Hs
		641506 PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69		CBP_HUMAN (643-1093): 3.52e-12: 73.4: 13.66
+	Hs
		211986 TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08		CHD7_HUMAN (536-874): 1.23e-30: 133: 12.83
+	Hs
		799133 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		CBP_HUMAN (643-1093): 3.52e-12: 73.4: 13.66
+	Hs
		203210 PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69		SYNJ1_HUMAN (493-887): 8.09e-09: 62.3: 10.70
+	Hs
		641616 PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69		CABIN_HUMAN (793-1075): 8.64e-09: 62.3: 16.04