Protein: XXLT1
Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)

Gene: XXLT1, XXYLT1
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q8NBI6

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0016266 - protein O-linked glycosylation via N-acetyl-galactosamine
GO:0030145 - manganese ion binding
GO:0035252 - UDP-xylosyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1047642

NOTC2
Neurogenic locus notch homolog protein 2

2

0

High-throughput

0.736

High

1194692

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.656

High

1333456

ZNT1
Proton-coupled zinc antiporter SLC30A1

3

6

High-throughput

0.643

High

951268

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.611

High

698890

CALX
Calnexin

1

5

High-throughput

0.536

High

522116

BCL2
Apoptosis regulator Bcl-2

1

0

High-throughput

0.513

High

888924

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

1306902

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.513

High

1315616

IZUM1
Izumo sperm-egg fusion protein 1

1

0

High-throughput

0.513

High

1322289

CLYBL
Citramalyl-CoA lyase, mitochondrial

1

0

High-throughput

0.513

High

701415

5HT1B
5-hydroxytryptamine receptor 1B

1

1

High-throughput

0.489

High

1114944

CUL4A
Cullin-4A

1

1

High-throughput

0.489

High

294029

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

1333435

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1333451

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

1249022

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1312556

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1333436

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.458

High

1333433

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.445

High

1333434

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.445

High

218469

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

372597

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406397

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

589176

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

695957

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768661

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1113720

CUL3
Cullin-3

1

1

High-throughput

0.437

High

1220656

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1254666

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1333446

T106B
Transmembrane protein 106B

1

2

High-throughput

0.437

High

301570

WFS1
Wolframin

1

0

High-throughput

0.426

High

211153

CTR4
Cationic amino acid transporter 4

1

1

High-throughput

0.407

High

535871

LAMC1
Laminin subunit gamma-1

1

2

High-throughput

0.407

High

624652

SL9A1
Sodium/hydrogen exchanger 1

1

1

High-throughput

0.407

High

722537

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.407

High

870386

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

1

High-throughput

0.407

High

1060370

SLC31
Amino acid transporter heavy chain SLC3A1

1

1

High-throughput

0.407

High

1132293

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.407

High

1233988

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

1

High-throughput

0.407

High

1242863

S39A4
Zinc transporter ZIP4

1

5

High-throughput

0.407

High

1251159

ZNT10
Calcium/manganese antiporter SLC30A10

1

6

High-throughput

0.407

High

1323723

S39AB
Zinc transporter ZIP11

1

5

High-throughput

0.407

High

1329177

S15A4
Solute carrier family 15 member 4

1

1

High-throughput

0.407

High

1333432

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

1333445

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

1

High-throughput

0.407

High

1333449

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.345

High

1333440

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.328

High

1333430

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

2

0

High-throughput

0.318

High

1023957

EM55
55 kDa erythrocyte membrane protein

2

0

High-throughput

0.313

High

1333438

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

1333441

PDD2L
Programmed cell death protein 2-like

2

0

High-throughput

0.313

High

1333453

PLAP
Phospholipase A-2-activating protein

2

0

High-throughput

0.313

High

165991

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

253517

ANM3
Protein arginine N-methyltransferase 3

1

0

High-throughput

0.279

Low

328383

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.279

Low

1179767

TYSD1
Peroxisomal leader peptide-processing protease

1

0

High-throughput

0.279

Low

1233764

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.279

Low

1333439

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.279

Low

1333442

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.279

Low

1333450

SPG21
Maspardin

1

0

High-throughput

0.279

Low

1333454

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.279

Low

1333455

TNPO3
Transportin-3

1

0

High-throughput

0.279

Low

831075

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

1220486

F219B
Protein FAM219B

1

0

High-throughput

0.249

Low

1333444

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1333448

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.249

Low

281622

MTX2
Metaxin-2

1

0

High-throughput

0.232

Low

577988

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.232

Low

712733

IL12A
Interleukin-12 subunit alpha

1

0

High-throughput

0.232

Low

1260376

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.232

Low

1308899

S22A9
Organic anion transporter 7

1

0

High-throughput

0.232

Low

1333431

ATAD1
Outer mitochondrial transmembrane helix translocase

1

0

High-throughput

0.232

Low

1333437

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.232

Low

1333443

CA198
Uncharacterized protein C1orf198

1

0

High-throughput

0.232

Low

1333447

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.232

Low

1333452

CCPG1
Cell cycle progression protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025