HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: OPTN (Q96CV9)
Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
Gene: OPTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34225486
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 577
+	Hs
		119112 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		LAMC1_HUMAN (59-543): 3.86e-30: 128: 13.64
+	Hs
		119211 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MYH10_HUMAN (233-561): 3.51e-13: 74.9: 10.88
+	Hs
		119210 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MYH9_HUMAN (171-574): 4.74e-10: 64.8: 13.08
+	Hs
		502812 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		LAMC1_HUMAN (59-543): 3.86e-30: 128: 13.64
+	Hs
		398168 LEG2_HUMAN (234-352): 1.96e-31: 117: 25.00		NEMO_HUMAN (204-576): 1.98e-39: 150: 25.86
+	Hs
		551634 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		DESP_HUMAN (6-522): 2.58e-16: 85.1: 11.60
+	Hs
		572299 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MYH10_HUMAN (233-561): 3.51e-13: 74.9: 10.88
+	Hs
		148313 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		CTRO_HUMAN (7-564): 1.03e-13: 76.6: 11.59
+	Hs
		254434 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		ROCK2_HUMAN (1-323): 2.95e-11: 68.7: 10.22
+	Hs
		449209 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		MYH9_HUMAN (171-574): 4.74e-10: 64.8: 13.08