HitPredict

Interactor 1: MPK17 (Q84M93)
Mitogen-activated protein kinase 17 (AtMPK17) (MAP kinase 17) (EC 2.7.11.24)
Gene: MPK17

Interactor 2: M2K10 (Q9LQM8)
Mitogen-activated protein kinase kinase 10 (AtMKK10) (MAP kinase kinase 10) (EC 2.7.12.2)
Gene: MKK10

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19513235
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Pkinase
Common GO terms	GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0106310 - protein serine kinase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 At			1 305
+	At
		1114822 MPK16_ARATH (2-481): 1.99e-168: 488: 63.54		CDPK8_ARATH (22-304): 4.93e-124: 366: 24.41
+	At
		1259034 MPK16_ARATH (2-481): 1.99e-168: 488: 63.54		CIPKN_ARATH (24-303): 2.48e-123: 363: 21.65
+	At
		1195620 MPK17_ARATH (1-486): 2.52e-180: 515: 100.00		M2K9_ARATH (1-303): 2.63e-109: 321: 42.31
+	At
		1321301 MPK15_ARATH (5-483): 5.7e-169: 490: 68.06		M2K7_ARATH (1-303): 6.55e-115: 335: 41.35
+	At
		1106684 MPK7_ARATH (10-358): 3.7e-145: 422: 42.98		CDPK8_ARATH (22-304): 4.93e-124: 366: 24.41
+	At
		1325301 MPK20_ARATH (2-485): 7.49e-160: 467: 62.19		M2K9_ARATH (1-303): 2.63e-109: 321: 42.31
+	At
		1106058 MPK2_ARATH (10-353): 1.53e-144: 420: 43.90		CDPK8_ARATH (22-304): 4.93e-124: 366: 24.41
+	At
		1106718 MPK7_ARATH (10-358): 3.7e-145: 422: 42.98		CIPKO_ARATH (39-303): 1.24e-119: 352: 20.80
+	At
		1259060 MPK16_ARATH (2-481): 1.99e-168: 488: 63.54		M2K2_ARATH (33-302): 6.37e-46: 160: 35.99
+	At
		285305 MPK4_ARATH (1-355): 1.93e-150: 435: 43.54		M2K4_ARATH (43-302): 3.6e-64: 207: 43.87
+	At
		285304 MPK3_ARATH (1-353): 7.66e-146: 423: 43.50		M2K4_ARATH (43-302): 3.6e-64: 207: 43.87
+	At
		1106332 MPK4_ARATH (1-355): 1.93e-150: 435: 43.54		M2K1_ARATH (31-303): 7.45e-51: 173: 35.86
+	At
		1106354 MPK4_ARATH (1-355): 1.93e-150: 435: 43.54		M2K6_ARATH (31-303): 1.52e-46: 162: 37.06
+	At
		1277206 MPK11_ARATH (1-352): 7.98e-146: 423: 43.06		M2K1_ARATH (31-303): 7.45e-51: 173: 35.86
+	At
		1106388 MPK4_ARATH (1-355): 1.93e-150: 435: 43.54		M2K2_ARATH (33-302): 6.37e-46: 160: 35.99
+	At
		1323812 MPK11_ARATH (1-352): 7.98e-146: 423: 43.06		M2K6_ARATH (31-303): 1.52e-46: 162: 37.06
+	At
		1338614 MPK11_ARATH (1-352): 7.98e-146: 423: 43.06		M2K2_ARATH (33-302): 6.37e-46: 160: 35.99
+	At
		1106733 MPK7_ARATH (10-358): 3.7e-145: 422: 42.98		M2K2_ARATH (33-302): 6.37e-46: 160: 35.99
+	At
		1106499 MPK5_ARATH (2-352): 1.43e-144: 420: 43.18		M2K2_ARATH (33-302): 6.37e-46: 160: 35.99
+	Hs
		1026805 MK07_HUMAN (4-373): 3.05e-144: 434: 44.12		MP2K5_HUMAN (47-302): 6.41e-37: 138: 32.83