HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	27173435, 33961781, 35271311, 24366813, 19615732, unassigned3799
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0016020 - membrane GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 89
+	Hs
		991558 AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00		DYL1_HUMAN (1-89): 1.81e-47: 147: 93.26
+	Hs
		991617 AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28		DYL1_HUMAN (1-89): 1.81e-47: 147: 93.26
+	Hs
		1314096 AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28		DYL2_HUMAN (1-89): 7.12e-47: 146: 100.00
+	Hs
		991777 AMOL2_HUMAN (296-902): 1.23e-28: 125: 40.92		DYL1_HUMAN (1-89): 1.81e-47: 147: 93.26
+	Hs
		1390761 AMOL2_HUMAN (296-902): 1.23e-28: 125: 40.92		DYL2_HUMAN (1-89): 7.12e-47: 146: 100.00
+	Hs
		991527 DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85		DYL1_HUMAN (1-89): 1.81e-47: 147: 93.26
+	Hs
		1123754 DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85		DYL2_HUMAN (1-89): 7.12e-47: 146: 100.00