Protein: AMOL2
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)

Gene: AMOL2, AMOTL2
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9Y2J4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001886 - endothelial cell morphogenesis
GO:0002102 - podosome
GO:0003365 - establishment of cell polarity involved in ameboidal cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862570

YAP1
Transcriptional coactivator YAP1

12

20

Small-scale

0.756

High

767381

MERL
Merlin

7

17

Small-scale

0.744

High

292408

RA51D
DNA repair protein RAD51 homolog 4

6

2

High-throughput

0.740

High

991777

DYL1
Dynein light chain 1, cytoplasmic

5

6

High-throughput

0.724

High

610514

PRS6A
26S proteasome regulatory subunit 6A

4

8

High-throughput

0.704

High

1160848

NFIL3
Nuclear factor interleukin-3-regulated protein

4

6

High-throughput

0.703

High

1325331

PALS1
Protein PALS1

4

12

Small-scale

0.699

High

1350751

CCHCR
Coiled-coil alpha-helical rod protein 1

4

19

High-throughput

0.698

High

1448721

LATS2
Serine/threonine-protein kinase LATS2

4

20

Small-scale

0.676

High

533309

THA
Thyroid hormone receptor alpha

3

14

High-throughput

0.675

High

1145936

RBP1
RalA-binding protein 1

3

18

High-throughput

0.675

High

1431531

CARD9
Caspase recruitment domain-containing protein 9

3

17

High-throughput

0.675

High

1461760

MYO5B
Unconventional myosin-Vb

3

16

High-throughput

0.675

High

1490790

AMOL2
Angiomotin-like protein 2

3

16

High-throughput

0.669

High

857058

GSTM5
Glutathione S-transferase Mu 5

4

0

High-throughput

0.668

High

1382648

MGN2
Protein mago nashi homolog 2

3

2

High-throughput

0.667

High

164138

NDC80
Kinetochore protein NDC80 homolog

3

18

High-throughput

0.666

High

1208659

BRM1L
Breast cancer metastasis-suppressor 1-like protein

3

0

High-throughput

0.646

High

618133

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.646

High

777415

K1C20
Keratin, type I cytoskeletal 20

2

20

High-throughput

0.646

High

1327483

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

1

High-throughput

0.646

High

300859

KRT38
Keratin, type I cuticular Ha8

2

20

High-throughput

0.644

High

691560

1433T
14-3-3 protein theta

3

20

High-throughput

0.643

High

730377

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.643

High

1197133

AMOT
Angiomotin

3

16

Small-scale

0.642

High

1371577

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

3

13

Small-scale

0.640

High

1217931

BRE1A
E3 ubiquitin-protein ligase BRE1A

4

15

High-throughput

0.637

High

1430229

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

2

17

Small-scale

0.634

High

299806

MPDZ
Multiple PDZ domain protein

2

20

High-throughput

0.628

High

1414544

HTAI2
Protein HTATIP2

2

1

High-throughput

0.628

High

1352431

SH3R2
E3 ubiquitin-protein ligase SH3RF2

4

15

High-throughput

0.623

High

272774

BRE1B
E3 ubiquitin-protein ligase BRE1B

3

18

High-throughput

0.616

High

935656

MFAP1
Microfibrillar-associated protein 1

3

2

High-throughput

0.616

High

1380038

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

3

1

High-throughput

0.616

High

132392

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

17

High-throughput

0.611

High

1386153

GCC1
GRIP and coiled-coil domain-containing protein 1

2

17

High-throughput

0.608

High

262451

DTNB
Dystrobrevin beta

2

4

High-throughput

0.606

High

302673

RNF8
E3 ubiquitin-protein ligase RNF8

2

11

High-throughput

0.606

High

407550

K2C1
Keratin, type II cytoskeletal 1

2

14

High-throughput

0.606

High

463266

YES
Tyrosine-protein kinase Yes

2

18

High-throughput

0.606

High

930821

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

9

High-throughput

0.606

High

1108867

BFSP2
Phakinin

2

20

High-throughput

0.606

High

1180047

CCD57
Coiled-coil domain-containing protein 57

2

19

High-throughput

0.606

High

1295624

RASL3
RAS protein activator like-3

2

14

High-throughput

0.606

High

1315805

DZI1L
Cilium assembly protein DZIP1L

2

20

High-throughput

0.606

High

1347418

LMO3
LIM domain only protein 3

2

10

High-throughput

0.606

High

1401274

FCRL5
Fc receptor-like protein 5

2

10

High-throughput

0.606

High

1437609

KIF9
Kinesin-like protein KIF9

2

20

High-throughput

0.606

High

1459017

DAXX
Death domain-associated protein 6

2

1

High-throughput

0.606

High

1490792

NDK7
Nucleoside diphosphate kinase homolog 7

2

2

High-throughput

0.606

High

967046

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

1049929

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

1390761

DYL2
Dynein light chain 2, cytoplasmic

2

6

High-throughput

0.601

High

1460871

FBX2
F-box only protein 2

2

5

High-throughput

0.601

High

1051438

ZBT16
Zinc finger and BTB domain-containing protein 16

2

0

High-throughput

0.580

High

1119044

BYST
Bystin

2

0

High-throughput

0.580

High

1136889

MO4L2
Mortality factor 4-like protein 2

2

0

High-throughput

0.580

High

1158613

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

252199

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.573

High

475728

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.573

High

572290

TRI27
Zinc finger protein RFP

1

11

High-throughput

0.573

High

659320

SP100
Nuclear autoantigen Sp-100

1

9

High-throughput

0.573

High

965528

LMO4
LIM domain transcription factor LMO4

1

10

High-throughput

0.573

High

992461

GBG5

1

3

High-throughput

0.573

High

1033445

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.573

High

1090986

TRAF2
TNF receptor-associated factor 2

1

17

High-throughput

0.573

High

1146220

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.573

High

1392960

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

2

High-throughput

0.573

High

1401191

SPAG5
Sperm-associated antigen 5

1

17

High-throughput

0.573

High

1419105

KRA42
Keratin-associated protein 4-2

1

1

High-throughput

0.573

High

1490433

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

3

High-throughput

0.573

High

373543

MYC
Myc proto-oncogene protein

2

19

High-throughput

0.571

High

991128

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

3

Small-scale

0.561

High

1432028

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

14

Small-scale

0.561

High

322883

MTCL2
Microtubule cross-linking factor 2

2

20

High-throughput

0.553

High

1042104

LMNB2
Lamin-B2

2

20

High-throughput

0.553

High

1150190

TCEA2
Transcription elongation factor A protein 2

2

2

High-throughput

0.553

High

1330184

CC185
Coiled-coil domain-containing protein 185

2

18

High-throughput

0.553

High

1380994

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

2

High-throughput

0.553

High

775483

DDIT3
DNA damage-inducible transcript 3 protein

1

0

High-throughput

0.549

High

1359842

RASF5
Ras association domain-containing protein 5

1

0

High-throughput

0.549

High

1431884

GO45
Golgin-45

1

0

High-throughput

0.549

High

249216

DSCAM
Cell adhesion molecule DSCAM

1

7

High-throughput

0.541

High

900563

FXR2
RNA-binding protein FXR2

1

7

High-throughput

0.541

High

964196

GBG11

1

3

High-throughput

0.541

High

1023991

EM55
55 kDa erythrocyte membrane protein

1

12

High-throughput

0.541

High

1490793

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

17

High-throughput

0.541

High

659642

CRCM
Colorectal mutant cancer protein

1

19

High-throughput

0.536

High

718918

CCND3
G1/S-specific cyclin-D3

1

1

High-throughput

0.536

High

789253

NUP62
Nuclear pore glycoprotein p62

1

9

High-throughput

0.536

High

861848

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

17

High-throughput

0.536

High

872909

SOX2
Transcription factor SOX-2

1

9

High-throughput

0.536

High

972159

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

1115633

ASPP2
Apoptosis-stimulating of p53 protein 2

1

20

High-throughput

0.536

High

1272600

CSN6
COP9 signalosome complex subunit 6

1

2

High-throughput

0.536

High

1341110

INADL
InaD-like protein

1

20

High-throughput

0.536

High

1353310

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.536

High

1414074

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

19

High-throughput

0.536

High

1450022

LIN7C
Protein lin-7 homolog C

1

20

High-throughput

0.536

High

1063715

GOGA2
Golgin subfamily A member 2

1

19

High-throughput

0.523

High

403042

ANXA1
Annexin A1

1

7

High-throughput

0.515

High

1449660

RN146
E3 ubiquitin-protein ligase RNF146

1

2

Small-scale

0.515

High

950143

KR105
Keratin-associated protein 10-5

1

1

High-throughput

0.515

High

128493

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.513

High

221767

TPPC3
Trafficking protein particle complex subunit 3

1

0

High-throughput

0.513

High

874072

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.513

High

974696

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

1358504

TPC14
Trafficking protein particle complex subunit 14

1

0

High-throughput

0.513

High

1400448

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.513

High

869809

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.508

High

718052

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

Small-scale

0.501

High

994426

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

13

Small-scale

0.501

High

1490791

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

756593

GALNS
N-acetylgalactosamine-6-sulfatase

1

2

High-throughput

0.489

High

1364845

F168A
Protein FAM168A

1

2

High-throughput

0.489

High

227716

SPOP
Speckle-type POZ protein

1

5

Small-scale

0.481

High

566323

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.481

High

848359

MAGA4
Melanoma-associated antigen 4

1

17

High-throughput

0.481

High

1333031

F184A
Protein FAM184A

1

20

High-throughput

0.481

High

1361186

PIBF1
Progesterone-induced-blocking factor 1

1

3

High-throughput

0.481

High

1460272

CYH4
Cytohesin-4

1

6

High-throughput

0.481

High

173580

XPO1
Exportin-1

1

5

High-throughput

0.479

High

332463

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

14

Small-scale

0.479

High

851827

NKX21
Homeobox protein Nkx-2.1

1

3

High-throughput

0.479

High

1095329

REST
RE1-silencing transcription factor

1

2

High-throughput

0.479

High

1141070

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1155925

EZH2
Histone-lysine N-methyltransferase EZH2

1

11

High-throughput

0.479

High

1220901

RN123
E3 ubiquitin-protein ligase RNF123

1

14

High-throughput

0.479

High

1256168

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1367632

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1429025

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1454778

HECW2
E3 ubiquitin-protein ligase HECW2

1

17

Small-scale

0.479

High

716243

ERP29
Endoplasmic reticulum resident protein 29

1

2

High-throughput

0.470

High

49915

A1A4E9
Keratin 13

1

20

High-throughput

0.470

High

59938

A2BDD9
AMOT protein

1

16

High-throughput

0.470

High

1066055

Q08AM8
E3 ubiquitin-protein ligase SH3RF2

1

15

High-throughput

0.470

High

1169443

Q1RN33
Melanoma antigen A 4

1

17

High-throughput

0.470

High

1194600

Q4G0R1
PIBF1 protein

1

3

High-throughput

0.470

High

1243411

Q6P9G8
Family with sequence similarity 184, member A

1

17

High-throughput

0.470

High

1359213

Q8WWE8
CYTH4 protein

1

5

High-throughput

0.470

High

522309

OSTP
Osteopontin

1

0

Small-scale

0.460

High

1156906

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

401726

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.445

High

648252

NDKB
Nucleoside diphosphate kinase B

1

2

High-throughput

0.445

High

1227740

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.445

High

1401142

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.445

High

1389632

SAAL1
Protein SAAL1

1

1

High-throughput

0.439

High

1451873

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.439

High

406814

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.437

High

1335789

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

3614

A0A0S2Z6H0
Zinc finger CCCH-type with G patch domain-containing protein

1

3

High-throughput

0.417

High

1258623

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.407

High

1187708

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1295134

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1406167

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

1415946

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.316

High

354267

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.299

High

4800

A0A1B0GWI1
Coiled-coil domain containing 196

1

0

High-throughput

0.268

Low

270120

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025