HitPredict

Interactor 1: RALYL (Q86SE5)
RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3)
Gene: RALYL

Interactor 2: PPIE (Q9UNP9)
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)
Gene: PPIE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pro_isomerase~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 301
+	Hs
		241386 HNRC1_HUMAN (6-288): 8.26e-54: 178: 46.15		PPIE_HUMAN (1-301): 5.5e-108: 317: 100.00
+	Hs
		432996 HNRPC_HUMAN (6-288): 2.55e-49: 167: 50.52		PPIE_HUMAN (1-301): 5.5e-108: 317: 100.00
+	Hs
		1356521 RALY_HUMAN (1-291): 2.63e-45: 156: 44.71		PPIE_HUMAN (1-301): 5.5e-108: 317: 100.00
+	Hs
		925150 TRA2B_HUMAN (3-140): 9.38e-32: 121: 22.60		PPIE_HUMAN (1-301): 5.5e-108: 317: 100.00
+	Hs
		516744 PABP1_HUMAN (9-103): 6.11e-14: 73.7: 22.77		PPIE_HUMAN (1-301): 5.5e-108: 317: 100.00
+	Hs
		432637 HNRPC_HUMAN (6-288): 2.55e-49: 167: 50.52		PPIA_HUMAN (137-300): 3.31e-63: 198: 66.46
+	Hs
		923771 RBM4_HUMAN (22-97): 1.02e-16: 81.1: 23.68		PPIA_HUMAN (137-300): 3.31e-63: 198: 66.46