HitPredict

Interactor 1: SDCG8 (Q86SQ7)
Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)
Gene: SDCCAG8

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	17355907
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030030 - cell projection organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 713 Hs			1 1164
+	Hs
		724899 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		1189773 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		1137871 MRCKA_HUMAN (247-703): 4.76e-46: 179: 16.22		MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78
+	Rn
		222472 MRCKA_RAT (247-703): 1.84e-48: 186: 16.22		MRCKA_RAT (415-804): 5.64e-14: 79.1: 8.05
+	Hs
		1137917 MRCKA_HUMAN (247-703): 4.76e-46: 179: 16.22		MRCKB_HUMAN (835-1162): 1.41e-15: 84.5: 6.67
+	Hs
		725191 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Rn
		222476 MRCKA_RAT (247-703): 1.84e-48: 186: 16.22		MRCKB_RAT (856-1164): 4.53e-12: 72.9: 10.10
+	Hs
		528395 MYH6_HUMAN (2-562): 4.09e-20: 98.2: 10.60		CACO1_HUMAN (620-1116): 8.08e-29: 126: 14.93
+	Hs
		725097 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH11_HUMAN (392-1122): 2.73e-28: 126: 8.64
+	Hs
		724687 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		528356 MYH6_HUMAN (2-562): 4.09e-20: 98.2: 10.60		MYH6_HUMAN (623-1102): 9.65e-21: 101: 14.55
+	Rn
		92843 ROCK2_RAT (153-707): 4.91e-16: 84.8: 12.41		CTRO_RAT (337-1025): 8.64e-25: 114: 9.83
+	Hs
		148461 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		528432 MYH13_HUMAN (2-595): 9.82e-21: 100: 8.85		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73
+	Mm
		93570 MYH9_MOUSE (4-494): 1.42e-17: 89.7: 8.79		DESP_MOUSE (718-1164): 2.9e-13: 77.2: 10.89
+	Hs
		502901 MYH6_HUMAN (2-562): 4.09e-20: 98.2: 10.60		MYH3_HUMAN (400-850): 1.77e-10: 67.9: 10.00
+	Hs
		725174 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		725189 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		725095 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43