Interactor 1: DHDDS (Q86SQ9)
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Cis-prenyltransferase subunit hCIT) (Epididymis tissue protein Li 189m)
Gene: DHDDS

Interactor 2: NGBR (Q96E22)
Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)
Gene: NUS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Prenyltransf~Prenyltransf
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006489 - dolichyl diphosphate biosynthetic process
GO:0019408 - dolichol biosynthetic process
GO:0045547 - dehydrodolichyl diphosphate synthase activity
GO:0046872 - metal ion binding
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 333
Hs

1 293
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024