HitPredict

Interactor 1: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Interactor 2: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1689 Hs			1 431
+	Hs
		1046639 PB1_HUMAN (1-1689): 0: 1223: 100.00		KLF9_HUMAN (294-381): 4.19e-30: 118: 68.18
+	Hs
		1199221 PB1_HUMAN (1-1689): 0: 1223: 100.00		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		1199187 PB1_HUMAN (1-1689): 0: 1223: 100.00		KLF6_HUMAN (244-376): 1.27e-24: 104: 43.61
+	Hs
		1199213 PB1_HUMAN (1-1689): 0: 1223: 100.00		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		316930 PB1_HUMAN (1-1689): 0: 1223: 100.00		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		641198 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		SP3_HUMAN (267-376): 1.82e-43: 164: 70.91
+	Hs
		434956 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		SP1_HUMAN (195-410): 2.85e-40: 155: 46.30
+	Hs
		847027 SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		846827 SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1254946 RERE_HUMAN (1238-1599): 6.18e-09: 63.2: 11.47		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		600223 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		435014 SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58		SP1_HUMAN (195-410): 2.85e-40: 155: 46.30
+	Hs
		631572 BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		316791 BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		1304983 BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55		KLF6_HUMAN (244-376): 1.27e-24: 104: 43.61
+	Hs
		1327668 BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		316987 BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68