Protein: DDX20
Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3)

Gene: DDX20
Organism: Homo sapiens
Interactions: 231
UniProt ID: Q9UHI6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0003677 - DNA binding
GO:0003724 - RNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1256689

GEMI5
Gem-associated protein 5

8

14

Small-scale

0.970

High

998209

NCBP1
Nuclear cap-binding protein subunit 1

2

4

High-throughput

0.776

High

1084928

SMN
Survival motor neuron protein

16

3

Small-scale

0.763

High

157781

GEMI2
Gem-associated protein 2

8

1

Small-scale

0.750

High

884100

GEMI4
Gem-associated protein 4

11

0

Small-scale

0.726

High

911990

RUXF
Small nuclear ribonucleoprotein F

5

13

Small-scale

0.724

High

1355473

STRAP
Serine-threonine kinase receptor-associated protein

5

17

High-throughput

0.718

High

442572

RU17
U1 small nuclear ribonucleoprotein 70 kDa

5

20

High-throughput

0.714

High

911764

RUXE
Small nuclear ribonucleoprotein E

4

2

Small-scale

0.703

High

1355469

DICER
Endoribonuclease Dicer

1

19

High-throughput

0.691

High

1333349

GEMI7
Gem-associated protein 7

5

0

High-throughput

0.688

High

1263372

GEMI6
Gem-associated protein 6

5

0

Small-scale

0.684

High

539175

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

8

Small-scale

0.681

High

912126

RUXG
Small nuclear ribonucleoprotein G

3

20

Small-scale

0.674

High

912585

SMD2
Small nuclear ribonucleoprotein Sm D2

3

5

Small-scale

0.674

High

240808

USO1
General vesicular transport factor p115

3

15

High-throughput

0.667

High

1355465

AGO2
Protein argonaute-2

3

20

Small-scale

0.664

High

1347576

GEMI8
Gem-associated protein 8

4

0

High-throughput

0.664

High

348165

MYC
Myc proto-oncogene protein

3

16

High-throughput

0.656

High

147827

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

3

High-throughput

0.628

High

1333308

PHAX
Phosphorylated adapter RNA export protein

2

1

High-throughput

0.628

High

387680

P53
Cellular tumor antigen p53

2

3

Small-scale

0.624

High

1355472

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

13

Small-scale

0.624

High

359084

CRYAB
Alpha-crystallin B chain

2

7

Small-scale

0.620

High

323266

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

15

High-throughput

0.618

High

328988

TOP3B
DNA topoisomerase 3-beta-1

1

3

High-throughput

0.618

High

583618

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.618

High

685088

STIP1
Stress-induced-phosphoprotein 1

1

10

High-throughput

0.618

High

802515

ATRX
Transcriptional regulator ATRX

1

20

High-throughput

0.618

High

994384

DHX9
ATP-dependent RNA helicase A

1

12

Small-scale

0.618

High

1052793

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

16

High-throughput

0.618

High

1172152

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.618

High

1305972

BARD1
BRCA1-associated RING domain protein 1

1

4

High-throughput

0.618

High

1355463

DDX20
Probable ATP-dependent RNA helicase DDX20

1

16

High-throughput

0.618

High

1355466

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.618

High

727083

FUS
RNA-binding protein FUS

2

20

High-throughput

0.611

High

395999

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

949215

LSM11
U7 snRNA-associated Sm-like protein LSm11

2

0

High-throughput

0.602

High

780274

CCNF
Cyclin-F

2

9

High-throughput

0.601

High

821072

PRC2A
Protein PRRC2A

2

16

Small-scale

0.600

High

1202571

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

0

High-throughput

0.585

High

283056

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

15

High-throughput

0.584

High

370651

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

840424

ERF
ETS domain-containing transcription factor ERF

1

3

Small-scale

0.561

High

912395

SMD1
Small nuclear ribonucleoprotein Sm D1

1

13

Small-scale

0.561

High

912750

SMD3
Small nuclear ribonucleoprotein Sm D3

1

13

Small-scale

0.561

High

1302149

DCR1C
Protein artemis

2

0

High-throughput

0.559

High

1288048

HDA11
Histone deacetylase 11

1

17

High-throughput

0.554

High

1273037

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.547

High

529864

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.541

High

331105

PAK4
Serine/threonine-protein kinase PAK 4

1

6

High-throughput

0.536

High

441389

RU2B
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.536

High

446828

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

448845

RU1C
U1 small nuclear ribonucleoprotein C

1

6

High-throughput

0.536

High

506671

BCR
Breakpoint cluster region protein

1

10

High-throughput

0.536

High

515308

KPSH1
Serine/threonine-protein kinase H1

1

2

High-throughput

0.536

High

786641

STA5A
Signal transducer and activator of transcription 5A

1

1

High-throughput

0.536

High

867482

ICLN
Methylosome subunit pICln

1

3

High-throughput

0.536

High

879862

TPTE
Putative tyrosine-protein phosphatase TPTE

1

2

High-throughput

0.536

High

928040

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

12

High-throughput

0.536

High

1054651

RBM39
RNA-binding protein 39

1

20

High-throughput

0.536

High

1076134

OASL
2'-5'-oligoadenylate synthase-like protein

1

9

High-throughput

0.536

High

1084655

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

20

High-throughput

0.536

High

1136852

FAXC
Failed axon connections homolog

1

2

High-throughput

0.536

High

1219094

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

5

High-throughput

0.536

High

1235830

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

19

High-throughput

0.536

High

1252820

ARRD2
Arrestin domain-containing protein 2

1

7

High-throughput

0.536

High

1272676

CSN5
COP9 signalosome complex subunit 5

1

15

High-throughput

0.536

High

1272840

FGF14
Fibroblast growth factor 14

1

2

High-throughput

0.536

High

1292277

AURKB
Aurora kinase B

1

10

High-throughput

0.536

High

1300571

PSKH2
Serine/threonine-protein kinase H2

1

4

High-throughput

0.536

High

1306172

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1355477

RPKL1
Ribosomal protein S6 kinase-like 1

1

12

High-throughput

0.536

High

1349366

SPN90
NCK-interacting protein with SH3 domain

1

0

High-throughput

0.530

High

246398

SCN2B
Sodium channel subunit beta-2

1

0

High-throughput

0.517

High

836064

GSK3B
Glycogen synthase kinase-3 beta

1

9

High-throughput

0.515

High

1070681

RNPS1
RNA-binding protein with serine-rich domain 1

1

20

High-throughput

0.515

High

1305307

PHB2
Prohibitin-2

1

8

High-throughput

0.515

High

1326451

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.515

High

152052

TOR1A
Torsin-1A

1

2

High-throughput

0.515

High

792057

HD
Huntingtin

1

3

High-throughput

0.515

High

840851

DYN2
Dynamin-2

1

4

High-throughput

0.515

High

848154

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.515

High

454773

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

834364

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

1030653

CLN3
Battenin

1

0

High-throughput

0.513

High

1184823

FA2H
Fatty acid 2-hydroxylase

1

0

High-throughput

0.513

High

1232294

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1233062

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1309158

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.513

High

1332038

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

1355464

NUFP1
FMR1-interacting protein NUFIP1

1

0

Small-scale

0.504

High

781238

ETV3
ETS translocation variant 3

1

3

Small-scale

0.501

High

1355144

PARP2
Poly [ADP-ribose] polymerase 2

1

2

Small-scale

0.501

High

987306

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

5

High-throughput

0.500

High

1302954

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

0

High-throughput

0.493

High

1251988

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.493

High

126654

P2Y10
Putative P2Y purinoceptor 10

1

3

High-throughput

0.489

High

719786

RADI
Radixin

1

4

High-throughput

0.489

High

1031105

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.489

High

1067646

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

1355476

NPTN
Neuroplastin

1

2

High-throughput

0.489

High

305090

SPN1
Snurportin-1

1

0

Small-scale

0.480

High

120047

AP3B1
AP-3 complex subunit beta-1

1

1

High-throughput

0.479

High

123071

MEN1
Menin

1

4

High-throughput

0.479

High

149392

CTRO
Citron Rho-interacting kinase

1

18

High-throughput

0.479

High

165096

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.479

High

165880

KDM6B
Lysine-specific demethylase 6B

1

14

Small-scale

0.479

High

167724

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

16

High-throughput

0.479

High

178032

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

228989

PRKN
E3 ubiquitin-protein ligase parkin

1

19

High-throughput

0.479

High

236120

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

13

High-throughput

0.479

High

260630

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.479

High

264653

MTX2
Metaxin-2

1

2

High-throughput

0.479

High

298864

UFL1
E3 UFM1-protein ligase 1

1

6

High-throughput

0.479

High

313366

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

4

High-throughput

0.479

High

326809

SNAI1
Zinc finger protein SNAI1

1

6

High-throughput

0.479

High

331897

NSD2
Histone-lysine N-methyltransferase NSD2

1

9

Small-scale

0.479

High

339094

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

375052

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

385674

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

430370

PROF1
Profilin-1

1

2

High-throughput

0.479

High

504913

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.479

High

509742

UBL4A
Ubiquitin-like protein 4A

1

12

High-throughput

0.479

High

551585

TFE2
Transcription factor E2-alpha

1

6

High-throughput

0.479

High

553996

RFA2
Replication protein A 32 kDa subunit

1

12

High-throughput

0.479

High

570155

CEBPB
CCAAT/enhancer-binding protein beta

1

16

High-throughput

0.479

High

603770

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

Small-scale

0.479

High

613293

ITA6
Integrin alpha-6

1

7

High-throughput

0.479

High

627388

MCM3
DNA replication licensing factor MCM3

1

8

High-throughput

0.479

High

652537

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

658450

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.479

High

680497

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

14

High-throughput

0.479

High

715012

PROF2
Profilin-2

1

2

High-throughput

0.479

High

719213

PHB1
Prohibitin 1

1

8

High-throughput

0.479

High

721713

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.479

High

771087

TCPZ
T-complex protein 1 subunit zeta

1

10

High-throughput

0.479

High

796451

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

3

High-throughput

0.479

High

815301

TISD
mRNA decay activator protein ZFP36L2

1

6

High-throughput

0.479

High

823510

PAXI
Paxillin

1

4

High-throughput

0.479

High

824506

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

828930

SRP09
Signal recognition particle 9 kDa protein

1

4

Small-scale

0.479

High

848995

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

1

High-throughput

0.479

High

863596

COPA
Coatomer subunit alpha

1

9

Small-scale

0.479

High

875761

MFAP1
Microfibrillar-associated protein 1

1

3

High-throughput

0.479

High

909287

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

943533

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.479

High

959747

VIGLN
Vigilin

1

16

High-throughput

0.479

High

967497

EWS
RNA-binding protein EWS

1

13

High-throughput

0.479

High

968000

PO5F1
POU domain, class 5, transcription factor 1

1

2

High-throughput

0.479

High

970048

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

1019160

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

1042775

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1054016

CAPR1
Caprin-1

1

3

High-throughput

0.479

High

1064237

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1064810

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.479

High

1066835

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1115763

CRY2
Cryptochrome-2

1

7

High-throughput

0.479

High

1168004

GGYF2
GRB10-interacting GYF protein 2

1

9

Small-scale

0.479

High

1188999

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1220834

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

1246194

COP1
E3 ubiquitin-protein ligase COP1

1

16

High-throughput

0.479

High

1255720

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.479

High

1260418

PDC6I
Programmed cell death 6-interacting protein

1

13

High-throughput

0.479

High

1260947

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

1267224

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

10

High-throughput

0.479

High

1267894

CNOT9
CCR4-NOT transcription complex subunit 9

1

2

High-throughput

0.479

High

1269860

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1273760

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

Small-scale

0.479

High

1285716

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.479

High

1286251

ARMC5
Armadillo repeat-containing protein 5

1

5

High-throughput

0.479

High

1293741

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.479

High

1294109

DDRGK
DDRGK domain-containing protein 1

1

7

High-throughput

0.479

High

1294882

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

13

Small-scale

0.479

High

1299405

RBM14
RNA-binding protein 14

1

17

High-throughput

0.479

High

1306730

TCPH
T-complex protein 1 subunit eta

1

7

High-throughput

0.479

High

1307042

ANM1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.479

High

1309717

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

11

High-throughput

0.479

High

1313249

TCAB1
Telomerase Cajal body protein 1

1

14

Small-scale

0.479

High

1316796

ACE2
Angiotensin-converting enzyme 2

1

7

High-throughput

0.479

High

1319110

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

6

High-throughput

0.479

High

1329019

P2Y12
P2Y purinoceptor 12

1

1

High-throughput

0.479

High

1331560

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1333788

ECT2
Protein ECT2

1

11

High-throughput

0.479

High

1334432

NANOG
Homeobox protein NANOG

1

2

High-throughput

0.479

High

1334985

BRF2
Transcription factor IIIB 50 kDa subunit

1

2

High-throughput

0.479

High

1335222

RC3H2
Roquin-2

1

12

High-throughput

0.479

High

1342821

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

1344521

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

1347619

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.479

High

1348122

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

Small-scale

0.479

High

1355467

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

1355468

CP131
Centrosomal protein of 131 kDa

1

5

High-throughput

0.479

High

1355470

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

1355471

HDAC5
Histone deacetylase 5

1

19

High-throughput

0.479

High

1355474

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.479

High

1355475

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

13

High-throughput

0.479

High

344582

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.470

High

750521

COIL
Coilin

1

0

High-throughput

0.458

High

894988

SRP54
Signal recognition particle subunit SRP54

1

0

Small-scale

0.458

High

1153678

ANO7
Anoctamin-7

1

0

Small-scale

0.458

High

1200246

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1235338

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.458

High

1295121

EAF1
ELL-associated factor 1

1

0

High-throughput

0.458

High

1332731

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1348140

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

Small-scale

0.458

High

1344811

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

48741

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.445

High

68466

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

20

High-throughput

0.445

High

402589

JUN
Transcription factor Jun

1

18

High-throughput

0.445

High

853999

NCBP2
Nuclear cap-binding protein subunit 2

1

20

High-throughput

0.445

High

1032668

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

1120484

NCBP3
Nuclear cap-binding protein subunit 3

1

4

High-throughput

0.445

High

1153435

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

1330658

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

12

High-throughput

0.445

High

995284

GOGA2
Golgin subfamily A member 2

1

9

High-throughput

0.437

High

1053682

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1159462

FBX42
F-box only protein 42

1

6

High-throughput

0.437

High

1198215

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1222118

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1348299

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

1347850

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

1157

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

99694

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1241666

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

1237331

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1328627

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1354055

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

118487

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

1166041

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024