HitPredict

Interactor 1: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36537216
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~PHD, Bromodomain~PHD
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1689 Hs			1 2004
+	Hs
		1018557 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		1199172 PB1_HUMAN (1-1689): 0: 1223: 100.00		DPF1_HUMAN (87-322): 3.58e-58: 208: 31.25
+	Hs
		1059704 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1199174 PB1_HUMAN (1-1689): 0: 1223: 100.00		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		1199173 PB1_HUMAN (1-1689): 0: 1223: 100.00		DPF3_HUMAN (95-310): 5.14e-50: 184: 30.32
+	Hs
		1199167 PB1_HUMAN (1-1689): 0: 1223: 100.00		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Mm
		101544 F8VQD1_MOUSE (1-1689): 0: 1207: 97.30		PHF10_MOUSE (200-318): 7.34e-42: 164: 46.77
+	Dm
		1179552 Q9VC36_DROME (1-1458): 0: 711: 34.35		Q7K3G5_DROME (193-318): 1.01e-41: 163: 48.03
+	Dm
		1362523 Q9VC36_DROME (1-1458): 0: 711: 34.35		SAYP_DROME (197-310): 8.15e-33: 142: 34.21
+	Hs
		641254 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Mm
		533916 DNMT1_MOUSE (294-1361): 5.18e-70: 263: 12.38		KAT5_MOUSE (292-779): 1.57e-131: 424: 34.82
+	Hs
		309660 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		309702 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Sc
		710449 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		SAS3_YEAST (486-860): 1.72e-122: 410: 32.69
+	Hs
		600135 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		641217 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1255033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD5_HUMAN (165-468): 3.23e-53: 209: 12.87
+	Hs
		1059760 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1059625 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1056838 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19