HitPredict

Interactor 1: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20130577
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1689 Hs			1 2997
+	Hs
		1018557 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		1059704 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		847007 PB1_HUMAN (1-1689): 0: 1223: 100.00		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Mm
		101533 F8VQD1_MOUSE (1-1689): 0: 1207: 97.30		SMCA4_MOUSE (232-1604): 0: 796: 22.79
+	Mm
		1111945 PB1_MOUSE (1-1689): 0: 1168: 91.95		SMCA4_MOUSE (232-1604): 0: 796: 22.79
+	Hs
		1199201 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD8_HUMAN (1-976): 4.16e-09: 65.1: 7.67
+	Hs
		229313 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		229448 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		229407 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		641217 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		600135 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		1255033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD5_HUMAN (670-1947): 0: 837: 25.68
+	Sc
		697424 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		CHD1_YEAST (815-1973): 0: 851: 28.88
+	Hs
		151436 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD1_HUMAN (650-1969): 0: 824: 25.71
+	Hs
		1059760 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Sc
		969433 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		ISW2_YEAST (783-1895): 0: 827: 25.83
+	Hs
		847093 BRWD1_HUMAN (2-959): 3.8e-58: 224: 12.26		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		151415 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		CHD1_HUMAN (650-1969): 0: 824: 25.71
+	Sc
		744895 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		ISW1_YEAST (822-1900): 0: 818: 26.26
+	Hs
		847033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		SMCA4_HUMAN (232-1604): 0: 790: 22.42