Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21715681
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0006809 - nitric oxide biosynthetic process
GO:0010628 - positive regulation of gene expression
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 839
Hs

1 178
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024