Protein: NUB1
NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)

Gene: NUB1
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9Y5A7

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0010498 - proteasomal protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1154973

NEDD8
Ubiquitin-like protein NEDD8

7

5

Small-scale

0.963

High

182007

UBD
Ubiquitin D

6

7

Small-scale

0.956

High

1098184

PSMD2
26S proteasome non-ATPase regulatory subunit 2

2

0

Small-scale

0.738

High

508902

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

Small-scale

0.724

High

1453522

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

4

1

Small-scale

0.703

High

507439

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

7

High-throughput

0.691

High

933762

PSMD4
26S proteasome non-ATPase regulatory subunit 4

4

0

Small-scale

0.668

High

584602

VAV
Proto-oncogene vav

2

1

High-throughput

0.628

High

243406

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.618

High

935349

TERA
Transitional endoplasmic reticulum ATPase

2

0

Small-scale

0.603

High

1491509

SNCAP
Synphilin-1

2

0

Small-scale

0.593

High

957697

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

0

Small-scale

0.589

High

891919

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.586

High

928601

TERF1
Telomeric repeat-binding factor 1

1

0

Small-scale

0.569

High

1148582

SF3B4
Splicing factor 3B subunit 4

1

0

High-throughput

0.549

High

1315662

RN168
E3 ubiquitin-protein ligase RNF168

1

1

High-throughput

0.536

High

954770

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.513

High

969101

PRS8
26S proteasome regulatory subunit 8

1

0

High-throughput

0.513

High

1356590

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

921840

COPB
Coatomer subunit beta

1

1

High-throughput

0.481

High

1370004

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

Small-scale

0.480

High

321708

PRP6
Pre-mRNA-processing factor 6

1

2

High-throughput

0.479

High

530663

TAU
Microtubule-associated protein tau

1

1

Small-scale

0.479

High

691584

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

730399

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

730991

1433S
14-3-3 protein sigma

1

6

High-throughput

0.479

High

872940

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

967077

1433G
14-3-3 protein gamma

1

6

High-throughput

0.479

High

990920

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

1049952

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

1436587

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

187579

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.460

High

414919

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

696975

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

700983

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

769617

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

972181

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

1067878

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1108323

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1115172

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1127619

FAT1
Protocadherin Fat 1

1

0

Small-scale

0.458

High

1397603

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1435503

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1459455

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1419989

CRNL1
Crooked neck-like protein 1

1

2

High-throughput

0.445

High

844137

HD
Huntingtin

1

0

High-throughput

0.438

High

1448597

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1235441

LCN8
Epididymal-specific lipocalin-8

1

0

High-throughput

0.279

Low

1420865

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

1256263

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1434341

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1460334

XPO7
Exportin-7

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025