HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: WDR33 (Q9C0J8)
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
Gene: WDR33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 1336
+	Hs
		1056974 MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73		WDR33_HUMAN (1-1324): 2.65e-176: 561: 96.13
+	Hs
		1302927 MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24		NLE1_HUMAN (35-455): 9.05e-104: 340: 20.00
+	Hs
		1346970 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		NLE1_HUMAN (35-455): 9.05e-104: 340: 20.00
+	Hs
		1222858 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		NLE1_HUMAN (35-455): 9.05e-104: 340: 20.00
+	Hs
		197050 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PRP4_HUMAN (275-480): 1.56e-28: 123: 16.13
+	Hs
		903347 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		WDR5_HUMAN (367-521): 5.01e-11: 67.7: 10.97
+	Rn
		870010 FNDC1_RAT (146-941): 7.74e-45: 178: 10.27		GBB2_RAT (218-502): 1.56e-42: 161: 17.59
+	Hs
		152663 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		WDR5B_HUMAN (23-315): 1.79e-74: 252: 15.71
+	Hs
		1281391 PRR36_HUMAN (6-923): 8.04e-16: 84.8: 8.61		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		1222816 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		793042 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		LIS1_HUMAN (284-476): 1.35e-37: 148: 18.65
+	Hs
		152678 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		1056609 TRIPC_HUMAN (539-925): 2.98e-10: 66.6: 17.28		FBXW7_HUMAN (229-428): 7.22e-42: 167: 21.89
+	Hs
		473762 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		C1T9A_HUMAN (602-773): 6.55e-19: 91.7: 38.67
+	Mm
		903669 KMT2C_MOUSE (260-934): 3.18e-12: 73.1: 17.15		WDR5_MOUSE (367-521): 5.01e-11: 67.7: 10.97
+	Hs
		152622 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		WDR5_HUMAN (367-521): 5.01e-11: 67.7: 10.97