HitPredict

Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 15107846, 33052227, 12646618, 10952994, 17258210, 18221795, 20048342, 21911421, 17228323, 12888566, 15728506, 17126326, 9625770, 19717524, 21829704
Identification Methods two hybrid, affinity chromatography technology, pull down, protein complementation assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006909 - phagocytosis
GO:0007254 - JNK cascade
and 25 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024